Methotrexate

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Leukoencephalopathy: case report It a retrospective study of 123 patients hospitalised between 1 August2018 to 31 July 2019 in India, one patient [age and sex not stated] was described, who developed leukoencephalopathy during treatment with methotrexate for acute lymphoblastic leukaemia. The patient, who had acute lymphoblastic leukaemia, started receiving treatment with Berlin-Frankfurt-Munster (BFM)ALL 95 chemotherapy protocol including methotrexate [route and dosage not stated]. Eventually, the patient was admitted with headache and was eventually diagnosed with leukoencephalopathy due to methotrexate [duration of treatment to reaction onste and outcome not stated]. Hasan F, et al. Cns complications in acute lymphoblastic leukemia: A tertiary carecentre experience from North India. Indian Journal of Hematology and Blood Transfusion 803503121 35 (Suppl.): S10, No. 1, Jan 2019. Available from: URL: http://doi.org/10.1007/s12288-019-01207-5 [abstract]

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Reactions 26 Sep 2020 No. 1823