Multiple drugs
- PDF / 169,927 Bytes
- 1 Pages / 595.245 x 841.846 pts (A4) Page_size
- 27 Downloads / 133 Views
1 S
Gingival enlargement: case report A 39-year-old man developed gingival enlargement while receiving treatment with ciclosporin, diltiazem, mycophenolate mofetil and prednisone [routes and indications not stated]. The man, who had undergone renal transplant in 2003, presented with severe gingival enlargement in October 2013. He had been receiving ciclosporin 100mg capsule twice daily, diltiazem 120mg capsule twice daily, prednisone 5mg tablet once daily and mycophenolate mofetil 250mg four capsules twice daily. Before the first visit, he had discontinued prednisone. He developed gingival enlargement within one year of renal transplantation and ciclosporin treatment. Also, he had several surgery excisions for treatment of gingival enlargement with recurrence. Periodontal examination showed generalised pseudopockets except in the regions of mandibular anterior teeth and interproximal area between maxillary right first and second molars. Radiographs revealed localised moderate bone loss in mandibular anterior teeth and interproximal area between maxillary right first and second molars. The man was treated with azithromycin, initial debridement and chlorhexidine along with instructed to follow strict oral hygiene measures. He returned after 3 days of debridement. He reported that within 24 hours of azithromycin, gingival enlargement clinically improved. He was continued with azithromycin and chlorhexidine for next 3 weeks. Minimal surgical therapy was required to return gingival enlargement to normal characteristics. He was unable to return for 18 month follow-up, due to the distance and work schedule. His physician prescribed azithromycin for recurrent respiratory infection. At this time, complete resolution of gingival enlargement was observed. Kumar SS, et al. Management of Cyclosporine-Influenced Gingival Enlargement With Azithromycin. Clinical Advances in Periodontics 10: 140-144, No. 3, Sep 2020. Available from: URL: http://doi.org/10.1002/cap.10097 803505989
0114-9954/20/1825-0001/$14.95 Adis © 2020 Springer Nature Switzerland AG. All rights reserved
Reactions 10 Oct 2020 No. 1825
Data Loading...
