Neurotoxicity of Metals
In this book, international authorities address contemporary research in metal neurotoxicity. Essential and non-essential metals play an important role in neurodevelopmental and neurodegenerative diseases. Recent developments in understanding the role of
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Michael Aschner Lucio G. Costa Editors
Neurotoxicity of Metals
Advances in Neurobiology Volume 18
Series Editor Arne Schousboe
More information about this series at http://www.springer.com/series/8787
Michael Aschner • Lucio G. Costa Editors
Neurotoxicity of Metals
Editors Michael Aschner Department of Molecular Pharmacology Albert Einstein College of Medicine Bronx, NY, USA
Lucio G. Costa Department of Environmental and Occupational Health Sciences University of Washington Seattle, WA, USA
ISSN 2190-5215 ISSN 2190-5223 (electronic) Advances in Neurobiology ISBN 978-3-319-60188-5 ISBN 978-3-319-60189-2 (eBook) DOI 10.1007/978-3-319-60189-2 Library of Congress Control Number: 2017953381 © Springer International Publishing AG 2017 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer International Publishing AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland
Contents
Part I Developmental Neurotoxicity evelopmental Neurotoxicity of Lead������������������������������������������������������������ 3 D Samuel Caito and Michael Aschner anganese and Developmental Neurotoxicity���������������������������������������������� 13 M Roberto Lucchini, Donatella Placidi, Giuseppa Cagna, Chiara Fedrighi, Manuela Oppini, Marco Peli, and Silvia Zoni I nherited Disorders of Manganese Metabolism�������������������������������������������� 35 Charles E. Zogzas and Somshuvra Mukhopadhyay Part II Neurodegenerative Disorders hemical Speciation of Selenium and Mercury as Determinant C of Their Neurotoxicity ������������������������������������������������������������������������������������ 53 C.S. Oliveira, B.C. Piccoli, M. Aschner, and J.B.T. Rocha Metals and Paraoxonases���������������������������
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