Palbociclib

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Various toxicities: 10 case reports In a prospective analysis of real-world use of palbociclib alongside endocrine therapy (RENATA study) in 128 patients between October 2015 and August 2019, for the treatment of hormone receptor-positive, HER-2 negative (HR+/HER2-), advanced, metastatic breast cancer, ten patients [ages and sexes not stated] were described, who developed abscessed pneumonia, acute colitis, pulmonary embolism, xerostomia, grade 1 cutaneous rash, grade 2 cutaneous rash, grade 2 hyperglycaemia, femoral head osteonecrosis, grade 1 acute blepharitis and grade 1 hand-foot syndrome (1 patient each) following treatment with palbociclib [routes, dosages, durations of treatments to reactions onsets and outcomes not stated]. Petracci F, et al. RENATA study-Latin American prospective experience: Clinical outcome of patients treated with palbociclib in hormone receptor-positive metastatic breast 803505074 cancer-real-world use. Ecancermedicalscience 14: 2020. Available from: URL: http://doi.org/10.3332/ECANCER.2020.1058

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Reactions 3 Oct 2020 No. 1824