Patients with Delayed Gastric Emptying Following Laparoscopic Repair of Large Hiatus Hernias Regain Long-Term Quality of
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RESEARCH COMMUNICATION
Patients with Delayed Gastric Emptying Following Laparoscopic Repair of Large Hiatus Hernias Regain Long-Term Quality of Life David S. Liu 1,2
&
Tim Bright 2,3 & Sarah K. Thompson 2,3 & Tanya Irvine 3 & David I. Watson 2,3 & Ahmad Aly 1,4
Received: 14 May 2020 / Accepted: 30 June 2020 # 2020 The Society for Surgery of the Alimentary Tract
Keywords Delayed gastric emptying . Hiatus hernia . Quality of life
Introduction Approximately 20% of patients develop delayed gastric 1 emptying (DGE) following large hiatus hernia repair. This incurs short-term morbidity, with our recent study 2 demonstrating poorer outcomes at 12 months post-surgery. However, the longer-term consequences of DGE are unclear. Here, we report the impact of DGE following laparoscopic repair of large hiatus hernia on quality of life, gastrointestinal symptomatology, daily function and overall satisfaction at 3 and 5 years follow-up.
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chest) were analysed. The short-term outcomes and study pro2 tocol have been reported elsewhere. As previously published, DGE was defined by endoscopic evidence of gastric food reten1 tion after > 6 h of fasting at 6 months post-surgery. , 2 Quality of life, symptomatology and functional assessments were undertaken at 1, 3 and 5 years post-surgery using the SF-36 questionnaire 2 (Table S1), Visick scoring and structured surveys. Groups were compared using Fisher’s exact test for categorical variables and one-way analysis of variance with Dunnett’s multiple comparison post-test for continuous variables. A twotailed p < 0.05 was considered statistically significant. Statistical analyses were conducted using Prism v7.0 (GraphPad, San Diego, California).
Methods Data from a multicenter randomized trial comparing sutured versus mesh repair of large hiatus hernias (> 50% of stomach in David I. Watson and Ahmad Aly are the Co-senior authors Trial Registration Registered with the Australia and New Zealand Clinical Trials Registry, ACTRN12605000725662 Electronic supplementary material The online version of this article (https://doi.org/10.1007/s11605-020-04733-0) contains supplementary material, which is available to authorized users. * David S. Liu [email protected] 1
Department of Surgery, Austin Hospital, Heidelberg, Victoria 3084, Australia
2
Oesophagogastric Unit, Flinders Medical Centre, Flinders Drive, Bedford Park, South Australia 5042, Australia
3
Flinders University Discipline of Surgery, Flinders Medical Centre, Bedford Park, South Australia 5042, Australia
4
University of Melbourne Department of Surgery, Austin Hospital, Heidelberg, Victoria 3084, Australia
Results Nineteen of 102 (18.6%) patients had DGE 6 months after surgery. The baseline characteristics between those who did and did not (controls) develop DGE were 1 1 similar. , 2 Mesh repair was not associated with DGE. SF-36 completion rates at 1 [DGE 14 (73.7%), control 70 (84.3%)], 3 [DGE 15 (78.9%), control (63 (75.9%)] and 5 years [DGE 13 (68.4%), controls 63 (75.9%)] were comparable between groups. Although pati
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