Phosphorescent Oxygen-Sensitive Probes
Biological O2 sensing probes and measurement techniques were first introduced in the late 80s. In the last 3-5 years they have undergone major development that have made them available and affordable for a broad range of applications in various discipline
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Dmitri B. Papkovsky Alexander V. Zhdanov Andreas Fercher Ruslan I. Dmitriev James Hynes •
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Phosphorescent Oxygen-Sensitive Probes
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Dmitri B. Papkovsky Department of Biochemistry University College Cork Cork Ireland
Ruslan I. Dmitriev Department of Biochemistry University College Cork Cork Ireland
Alexander V. Zhdanov Department of Biochemistry University College Cork Cork Ireland
James Hynes Luxcel Biosciences Ltd. BioInnovation Centre, UCC Cork Ireland
Andreas Fercher Department of Biochemistry University College Cork Cork Ireland
ISSN 2211-9353 ISBN 978-3-0348-0524-7 DOI 10.1007/978-3-0348-0525-4
ISSN 2211-9361 (electronic) ISBN 978-3-0348-0525-4 (eBook)
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Preface
Measurement of dissolved oxygen concentration in biological samples by luminescence quenching method has been introduced by the pioneering work of German scientists Dietrich Lubbers and Norbert Opitz who developed in the mid1970s first solid-state fluorescence-based O2 sensors called ‘optodes’, and by the group of David Wilson in the US who introduced the phosphor
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