Ponatinib

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Cerebral haemorrhage: case report A multi-centre, observational retrospective analysis (Observatory of Ponatinib in Acute Lymphoblastic leukaemia; OPAL study) of 29 patients described a patient [age and sex not stated], who experienced a fatal cerebral haemorrhage during treatment with ponatinib for relapsed/refractory Philadelphia chromosome-positive acute lymphoblastic leukaemia [dosage, route and duration of treatment to reaction onset not stated]. Tavitian S, et al. Ponatinib-based therapy in adults with relapsed or refractory Philadelphia chromosome-positive acute lymphoblastic leukemia: results of the real-life OPAL 803507958 study. Leukemia and Lymphoma 61: 2161-2167, No. 9, 28 Jul 2020. Available from: URL: http://doi.org/10.1080/10428194.2020.1762876

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Reactions 17 Oct 2020 No. 1826