Postoperative analgesic efficacy of modified continuous transversus abdominis plane block in laparoscopic colorectal sur
- PDF / 1,242,942 Bytes
- 9 Pages / 595.276 x 790.866 pts Page_size
- 6 Downloads / 238 Views
ORIGINAL ARTICLE
Postoperative analgesic efficacy of modified continuous transversus abdominis plane block in laparoscopic colorectal surgery: a triple‑blind randomized controlled trial P. Haruethaivijitchock1 · J. L. Ng2 · G. Taksavanitcha1 · J. Theerawatanawong1 · T. Rattananupong3 · V. Lohsoonthorn3 · C. Sahakitrungruang4 Received: 23 November 2019 / Accepted: 16 July 2020 © Springer Nature Switzerland AG 2020
Abstract Background The optimal opioid-sparing analgesic regimen following laparoscopic colorectal surgery (LCS) remains uncertain. We sought to determine the efficacy of low-dose bupivacaine infusion via surgeon-inserted modified continuous transversus abdominis plane (mcTAP) catheters after LCS. Methods A parallel-group, placebo-controlled, randomized single-centre trial was conducted between April 2017 and February 2018. Block-of-four randomization and allocation concealment by sequentially-numbered, opaque sealed envelopes were used. Patients, surgeons and assessors were blinded. Fifty-two patients were randomized to receive either 0.2% bupivacaine or saline through mcTAP catheters. A 5 ml bolus followed by a 72 h infusion at 2 ml/h was started, with patient-controlled fentanyl analgesia and oral paracetamol given on demand. Primary outcomes were fentanyl consumptions in the first 24 h, second 24 h, and third 24 h following surgery. Secondary outcomes were pain numeric rating scores, recovery outcomes and complications. Results Twenty-five patients in the bupivacaine group and 26 in the control group were analysed. Patients in the bupivacaine group required significantly less fentanyl overall (106.1 vs 484.5 mcg, p
Data Loading...
