Predictive factors of posttreatment fracture by definitive radiotherapy for uterine cervical cancer
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ORIGINAL ARTICLE
Predictive factors of posttreatment fracture by definitive radiotherapy for uterine cervical cancer Kazuki Ishikawa1 · Tsuneo Yamashiro1 · Takuro Ariga1,2 · Takafumi Toita1,3 · Wataru Kudaka4 · Joichi Heianna1 · Hitoshi Maemoto1 · Takeaki Kusada1 · Wataru Makino1 · Yoichi Aoki4 · Sadayuki Murayama1 Received: 15 February 2020 / Accepted: 26 August 2020 © The Author(s) 2020
Abstract Purpose Fractures are known to shorten life expectancy and worsen the quality of life. The risk of fractures after radiation therapy in cervical cancer patients is known to be multifactorial. In this study, we examined risk factors for fractures in cervical cancer patients, especially by evaluating bone densities and DVH parameters for fractured bones. Materials and Methods For 42 patients, clinical characteristics, pretreatment CT bone densities, and radiation dose were compared between patients with and without fractures. Results Posttreatment fractures occurred in 25 bones among ten patients. Pretreatment CT bone densities were significantly lower in patients with fractures (P
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