Prevalence, seroconversion and mother-to-child transmission of dual and triplex infections of HIV, hepatitis B and C vir
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STUDY PROTOCOL
Open Access
Prevalence, seroconversion and mother-tochild transmission of dual and triplex infections of HIV, hepatitis B and C viruses among pregnant women in Nigeria: study protocol George Uchenna Eleje1,2* , Ikechukwu Innocent Mbachu1,2 , Uchenna Chukwunonso Ogwaluonye3 , Stephen Okoroafor Kalu4 , Chinyere Ukamaka Onubogu5 , Sussan Ifeyinwa Nweje6 , Chinwe Elizabeth Uzochukwu7 , Chike Henry Nwankwo8 , Preye Owen Fiebai9,10 , Olabisi Morebise Loto11,12 , Godwin Otuodichinma Akaba13,14 , Hadiza Abdullahi Usman15,16 , Ayyuba Rabiu17,18 , Richard Obinwanne Egeonu2 , Odion Emmanuel Igue19 , Bukola Abimbola Adesoji20 , Chiamaka Henrietta Jibuaku3 , Prince Ogbonnia Aja21 , Chiamaka Perpetua Chidozie21 , Hadiza Sani Ibrahim18 , Fatima Ele Aliyu18 , Aisha Ismaila Numan16 , Ogbonna Dennis Okoro22 , Solace Amechi Omoruyi10 , Ijeoma Chioma Oppah10 , Ubong Inyang Anyang14 , Aishat Ahmed14 , Shirley Nneka Chukwurah23, Osita Samuel Umeononihu1,2 , Rebecca Chinyelu Chukwuanukwu21 , Eric Okechukwu Umeh24 , Ekene Agatha Emeka25 , Chukwuanugo Nkemakonam Ogbuagu26 , Ibrahim Adamu Yakasai17,18 , Oliver Chukwujekwu Ezechi27 , Joseph Ifeanyichukwu Ikechebelu1,2 and Triplex infection in pregnancy collaboration group
Abstract Background: Nigeria contributes significantly to the global burden of HIV, Hepatitis B and C infections, either singly or in combinations, despite progress in HIV care regionally and globally. Although some limited data on mono infection of HIV, Hepatitis B and C virus infections do exists, that of dual and triplex infections, including seroconversion and mother-to-child transmission (MTCT) rates necessary for planning to address the scourge of infections in pregnancy are not available. Objectives: To determine the seroprevalence, rate of new infections, MTCT of dual and triple infections of HIV, Hepatitis B and C viruses and associated factors, among pregnant women in Nigeria. (Continued on next page)
* Correspondence: [email protected] 1 Department of Obstetrics and Gynecology, Nnamdi Azikiwe University, Awka, Nigeria 2 Department of Obstetrics and Gynecology, Nnamdi Azikiwe University Teaching Hospital, PMB 5025, Nnewi, Anambra State, Nigeria Full list of author information is available at the end of the article © The Author(s). 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To v
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