Quality of life in post-menopausal osteoporosis
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Quality of life in post-menopausal osteoporosis Maria Luisa Bianchi*1, Maria Rosa Orsini2, Silvia Saraifoger1, Sergio Ortolani1, Giovanni Radaelli3 and Simonetta Betti2 Address: 1Bone Metabolic Unit, Istituto Auxologico Italiano, IRCSS, Milan, Italy, 2Institute of Psychology, Medical Faculty, University of Milano, Milan, Italy and 3Unit of Medical Statistics, San Paolo Hospital, University of Milan, Italy Email: Maria Luisa Bianchi* - [email protected]; Maria Rosa Orsini - [email protected]; Silvia Saraifoger - [email protected]; Sergio Ortolani - [email protected]; Giovanni Radaelli - [email protected]; Simonetta Betti - [email protected] * Corresponding author
Published: 01 December 2005 Health and Quality of Life Outcomes 2005, 3:78
doi:10.1186/1477-7525-3-78
Received: 06 August 2005 Accepted: 01 December 2005
This article is available from: http://www.hqlo.com/content/3/1/78 © 2005 Bianchi et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract Background: To evaluate the impact of osteoporosis on the patients' quality of life, particularly in the absence of fractures. Methods: 100 post-menopausal women (age 50-85) - 62 with uncomplicated primary osteoporosis and 38 with primary osteoporosis complicated by vertebral fractures; all already treated - were studied using two validated questionnaires: Qualeffo-41 for quality of life in osteoporosis, and Zung for depression. Data were compared to those of 35 controls of comparable age, affected by a different chronic disease (hypothyroidism). Results: Family history of osteoporosis and T-score of spine were similar in the two subgroups of osteoporotic women. Body mass index, age at menopause and education level were similar in the two subgroups of osteoporotic women and in the control group. The patients affected by osteoporosis perceived it as a disease affecting their personal life with undesirable consequences: chronic pain (66% of women with fractures and 40% of women without fractures), impaired physical ability, reduced social activity, poor well-being (21% of women without fractures) and depressed mood (42% of women irrespective of fractures). Overall, 41% of the women showed a reduced quality of life. On the contrary, in the control group only 11% reported a reduced quality of life. Conclusion: The quality of life of osteoporotic patients should be investigated even before fractures, in order to develop appropriate counselling, support and care interventions to help patients develop efficient strategies for accepting the disease and coping with it.
Background Osteoporosis is a very common disease of bone, and fragility fractures (i.e. fractures in the absence of relevant trauma) are its typical complication and the most common pr
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