Radiographic Assessment of Meningiomas
Meningiomas are the most common primary brain tumor in adults, and, as such, we have a vast amount of knowledge and experience with the radiographic findings in these patients. For the majority of patients, standard imaging techniques of CT and MRI can re
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Meningiomas
Jennifer Moliterno • Antonio Omuro Editors
Meningiomas Comprehensive Strategies for Management
Editors Jennifer Moliterno Department of Neurosurgery Yale School of Medicine Yale New Haven Hospital New Haven, CT USA
Antonio Omuro Department of Neurology Yale School of Medicine Yale New Haven Hospital New Haven, CT USA
ISBN 978-3-030-59557-9 ISBN 978-3-030-59558-6 (eBook) https://doi.org/10.1007/978-3-030-59558-6 © Springer Nature Switzerland AG 2020 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, expressed or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Switzerland AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland
We dedicate this book to all patients impacted by a meningioma diagnosis, and especially share our hope for more promising treatment with those who suffer from more aggressive ones. Jennifer Moliterno Antonio Omuro
Preface
Meningiomas are one of the most common types of brain tumors and frequently encountered by primary care physicians and brain tumor specialists alike. While these tumors are more often histologically benign (i.e., WHO Grade 1), approximately 15–20% can behave atypical (i.e., WHO Grade 2) or frankly malignant (i.e., WHO Grade 3). Some Grade 1 tumors may never become symptomatic and can be relatively simple to manage. However, for others, as they grow along certain locations of the dura and skull base, oftentimes invading the skull, they can become quite debilitating to patients based on their location, size, and mass effect on and/or involvement of critical neurovascular structures. Thus, for certain “histologically benign” tumors, their clinical behavior may be anything but benign. Tumor recurrence, seen more frequently with Grades 2 and 3 meningiomas, but also with Grade 1 tumors, can be difficult to predict and poses many challenges for treating p
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