Retraction Note: Endoplasmic reticulum stress triggers Xanthoangelol-induced protective autophagy via activation of JNK/

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(2020) 39:164

RETRACTION NOTE

Open Access

Retraction Note: Endoplasmic reticulum stress triggers Xanthoangelol-induced protective autophagy via activation of JNK/ c-Jun Axis in hepatocellular carcinoma Zichao Li1, Luying Zhang2, Mingquan Gao3, Mei Han2, Kaili Liu2, Zhuang Zhang4, Zhi Gong4, Lifei Xing2, Xianzhou Shi5, Kui Lu4* and Hui Gao2* Retraction note to: J Exp Clin Cancer Res 38, 8 (2019) https://doi.org/10.1186/s13046-018-1012-z The Editor-in-Chief has retracted this article [1] due to overlapping images with other articles, specifically:  Figure 8d: the Beclin1 Vehicle and XAG (80 mg/kg)



 



panels appear to overlap with the cleaved caspase-3 Vehicle and Exanthone (80 mg/kg/day) panels of Fig. 7c of [2]. Figure 8d: the p-c-Jun Vehicle panel appears to overlap with the Beclin Vehicle panel of Fig. 7c of [2]. Figure 3a: the Bel7402 XAG + 3-MA panel appears to be identical to the SMMC7721 Vehicle panel. Figure 3c: the Bel7402 XAG + Atg5 siRNA panel appears to be identical to the SMMC7721 Vehicle panel. Figure 3c: the SMMC7721 Atg5 siRNA panel appears to be similar to the SKOV3 Control and A2780 Control panels of Fig. 1e of [3], the Vehicle panel of Fig. 4b in [4] and the HT29 Control panel of Fig. 7b of [5]

The original article can be found online at https://doi.org/10.1186/s13046018-1012-z. * Correspondence: [email protected]; [email protected] 4 China International Science and Technology Cooperation Base of Food Nutrition/Safety and Medicinal Chemistry, College of Biotechnology, Tianjin University of Science & Technology, Tianjin 300457, China 2 Department of Pharmacology, School of Pharmacy, Qingdao University, Qingdao 266021, China Full list of author information is available at the end of the article

 Figure 8d: the Vehicle CHOP, GRP78 and p-JNK

panels appears to be similar to the Ki-67 EX(40 mg/ kg) panel, the IL-18 Vehicle panel and the IL-18 EX(20 mg/kg) panel of [6].  Figure 8d: the XAG(40 mg/kg) CHOP panel appears to be similar to the KI-67 EX(20 mg/kg) panel of [6].  Figure 8d: the XAG(80 mg/kg) CHOP and GRP78 panels appear to be similar to the KI-67 Vehicle and the IL-18 EX(40 mg/kg) panels of [6]. The data reported in this article are therefore unreliable. Hui Gao agrees to this retraction. Zichao Li, Luying Zhang, Mingquan Gao, Mei Han, Kaili Liu, Zhuang Zhang, Zhi Gong, Lifei Xing, Xianzhou Shi, Kui Lunot have responded to any correspondence from the publisher about this retraction. Author details 1 College of Life Sciences, Qingdao University, Qingdao 266071, China. 2 Department of Pharmacology, School of Pharmacy, Qingdao University, Qingdao 266021, China. 3The Affiliated Cancer Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu 610041, Sichuan, China. 4China International Science and Technology Cooperation Base of Food Nutrition/Safety and Medicinal Chemistry, College of Biotechnology, Tianjin University of Science & Technology, Tianjin 300457, China. 5Northeast Yucai Bilingual School, Shenyang 110164, China.

References 1. Li Z,