Robust and conductive hydrogel based on mussel adhesive chemistry for remote monitoring of body signals
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ISSN 2223-7690 CN 10-1237/TH
RESEARCH ARTICLE
Robust and conductive hydrogel based on mussel adhesive chemistry for remote monitoring of body signals Weijun LI1,§, Hao LIU1,§, Yuanyuan MI1, Miaoran ZHANG1, Jinmiao SHI1, Ming ZHAO1, Melvin A. RAMOS2, Travis Shihao HU2, Jianxiong LI3, Meng XU3, Quan XU1,* 1
State Key Laboratory of Heavy Oil Processing, Beijing Key Laboratory of Biogas Upgrading Utilization, Harvard SEASCUPB Joint Laboratory on Petroleum Science, China University of Petroleum, Beijing 102249, China
2
Department of Mechanical Engineering, California State University, Los Angeles, CA 90032, USA
3
Department of Orthopedics General Hospital of Chinese People’s Liberation Army, Beijing 100853, China
§
These authors contributed equally to this work.
Received: 20 May 2020 / Revised: 01 June 2020 / Accepted: 09 June 2020
© The author(s) 2020. Abstract: There is a high demand for hydrogels with multifunctional performance (a combination of adhesive, mechanical, and electrical properties) in biological, tissue engineering, robotics, and smart device applications. However, a majority of existing hydrogels are relatively rigid and brittle, with limited stretchability; this hinders their application in the emerging field of flexible devices. In this study, cheap and abundant potato residues were used with polyacrylamide (PAM) to fabricate a multifunctional hydrogel, and chitosan was used for the design of a three-dimentional (3D) network-structured hydrogel. The as-prepared hydrogels exhibited excellent stretchability, with an extension exceeding 900% and a recovery degree of over 99%. Due to the combination of physical and chemical cross-linking properties and the introduction of dopamine, the designed hydrogel exhibits a remarkable self-healing ability (80% mechanical recovery in 2 h), high tensile strength (0.75 MPa), and ultra-stretchability (900%). The resultant products offer superior properties compared to those of previously reported tough and selfhealing hydrogels for wound adhesion. Chitosan and potato residues were used as scaffold materials for the hydrogels with excellent mechanical properties. In addition, in vitro experiments show that these hydrogels feature excellent antibacterial properties, effectively hindering the reproduction of bacteria. Moreover, the ternary hydrogel can act as a strain sensor with high sensitivity and a gauge factor of 1.6. The proposed strategy is expected to serve as a reference for the development of green and recyclable conductive polymers to fabricate hydrogels. The proposed hydrogel can also act as a suitable strain sensor for bio-friendly devices such as smart wearable electronic devices and/or for health monitoring. Keywords: bionic mussel; hydrogel; waste potato residues; adhesion; conductivity
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Introduction
Polymer hydrogels can integrate multiple functions in one design, including toughness, viscosity, selfhealing, electrical conductivity, and responsiveness, thus widening the range of applications in tissue * Corresponding author: Quan XU, E-mail
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