The Biofilm Primer
This book details the widely accepted hypothesis that the majority of bacteria in virtually all ecosystems grow in matrix-enclosed biofilms. The author, who proposed this biofilm hypothesis, uses direct evidence from microscopy and from molecular techniqu
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The Biofilm Primer Volume Author: J. William Costerton
With 67 Figures, 37 in color
123
Series Editor and Volume Author: Dr. J. William Costerton Director, Center for Biofilms School of Dentistry University of Southern California 925 West 34th Street Los Angeles, CA 90089 USA
Library of Congress Control Number: 2006939146
ISSN 1863-9607 ISBN 978-3-540-68021-5 Springer Berlin Heidelberg New York DOI 10.1007/b136878
This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilm or in any other way, and storage in data banks. Duplication of this publication or parts thereof is permitted only under the provisions of the German Copyright Law of September 9, 1965, in its current version, and permission for use must always be obtained from Springer. Violations are liable for prosecution under the German Copyright Law. Springer is a part of Springer Science+Business Media springer.com c Springer-Verlag Berlin Heidelberg 2007 The use of registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. Editor: Dr. Christina Eckey, Heidelberg Desk Editor: Anette Lindqvist, Heidelberg Cover design: Boekhorst Design BV, The Netherlands Typesetting and Production: LE-TEX Jelonek, Schmidt & Vöckler GbR, Leipzig Printed on acid-free paper 149/3100 YL – 5 4 3 2 1 0
Preface
Most human activities require a framework that may begin with a kindergarten, extend through sports, and culminate in the medieval institution of a university devoted to teaching, scholarly pursuits, and physical and emotional aggrandizement of its members. There is a certain pleasant symmetry in fitting into this framework being seen as a competent scholar, a journeyman athlete, and a member-in-good-standing of a collegial group that teaches bright youngsters and extends the boundaries of human perception. You play the game by its sensible and evolving rules, the endorphins flow, and you pass contented through the “seven stages of man.” I was blessed to have chosen a warm and wonderful wife who would let me disappear to climb a mountain, or write a grant, and then have our wonderful children all excited to “do something interesting” when Daddy returned. Janet Halliwell customized science funding in Canada, my lab at the new and vigorous University of Calgary grew to more than 40 people and multimillion-dollar funding, and Kan Lam managed the whole group so effectively that we drove the biofilm field forward with 38 refereed papers in a single year (1987). The pace was frantic, the team was winning and the atmosphere heady, and we poured over the goal line like a rugby team on steroids. But the rules of the game limited us to detailed incremental papers and tightly referenced reviews, biofilm perceptions jerked forward un
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