The gait disorder in primary orthostatic tremor

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The gait disorder in primary orthostatic tremor Ken Möhwald1,2   · Max Wuehr1 · Fabian Schenkel1 · Katharina Feil1,2 · Michael Strupp1,2 · Roman Schniepp1,2 Received: 15 March 2020 / Revised: 16 August 2020 / Accepted: 18 August 2020 © The Author(s) 2020

Abstract Objective  To uncover possible impairments of walking and dynamic postural stability in patients with primary orthostatic tremor (OT). Methods  Spatiotemporal gait characteristics were quantified in 18 patients with primary OT (mean age 70.5 ± 5.9 years, 10 females) and 18 age-matched healthy controls. One-third of patients reported disease-related fall events. Walking performance was assessed on a pressure-sensitive carpet under seven conditions: walking at preferred, slow, and maximal speed, with head reclination or eyes closed, and while performing a cognitive or motor dual-task paradigm. Results  Patients exhibited a significant gait impairment characterized by a broadened base of support (p = 0.018) with increased spatiotemporal gait variability (p = 0.010). Walking speed was moderately reduced (p = 0.026) with shortened stride length (p = 0.001) and increased periods of double support (p = 0.001). Gait dysfunction became more pronounced during slow walking (p