The Ion-Conducting Pore of Glutamate Receptor Channels
Ionotropic glutamate receptors (GluRs) mediate the postsynaptic response at most excitatory synapses in the brain. A variety of G1uR channel subtypes provides these synapses with a repertoire of distinct computational properties, many of which arise from
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Volume 141 Editorial Board G. Y.R. Born, London P. Cuatrecasas, Ann Arbor, MI D. Ganten, Berlin H. Herken, Berlin K. Starke, Freiburg 1. Br. P. Taylor, La Jolla, CA
Springer-Verlag Berlin Heidelberg GmbH
Ionotropic Glutamate Receptors in the eNS Contributors G. Adelmann, R. Bahring, P. B6h6, D. Bowie, nw. Choi, D. Colquhoun, M. Frotscher, R. Ganel, IR.P. Geiger, R. Gill, M. Hollmann, R.L. Huganir, P. Jonas, M.P. Kavanaugh, IA. Kemp, M.B. Kennedy, G.A. Kerchner, IN.C. Kew, A.H. Kim, H.-C. Kornau, T. Kuner, H.-K. Lee, I Lerma, M.L. Mayer, K. Mews, H. Monyer, T.S. Otis, R.S. Petralia, I Rossier, A. Roth, ID. Rothstein, M.E. Rubio, B. Sakmann, P.H. Seeburg, B. Taskin, L.a. Trussell, R.I Wenthold, L.P. Wollmuth, D.IA. Wyllie
Editors
Peter Jonas and Hannah Monyer
Springer
Professor Dr. Peter JONAS Albert -Ludwigs-U niversitat Freiburg Physiologisches 1nstitut Hermann-Herder-Str. 7 D-79104 Freiburg Germany e-mail: [email protected] Professor Dr. Hannah MONYER 2MBH, 1m Neuenheimer Feld 282 D-69120 Heidelberg Germany e-mail: [email protected]
With 70 Figures and 38 Tables ISBN 978-3-642-08539-0 Library of Congress Cataloging-in-Publication Data applied for Die Deutsche Bibliothek - CIP-Einheitsaufnahme Ionotropic glutamate receptors in the CNS 1 contributors G. Adelmann ... Ed. Peter Jonas and Hannah Monyer. (Handbook of experimental pharmacology; Vol. 141) ISBN 978-3-642-08539-0 ISBN 978-3-662-08022-1 (eBook) DOI 10.1007/978-3-662-08022-1
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Preface
It is now widely accepted that glutamate is the major excitatory neurotrans-
mitter in the mammalian central nervous system. The
