The New Coronavirus COVID-19 Infection
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The New Coronavirus COVID-19 Infection M. R. Bevovaa, S. V. Netesovb, and Yu. S. Aulchenkob, c, * a
University of Liège, Liège, 4000 Belgium Novosibirsk State University, Novosibirsk, 630090 Russia c Federal Research Center Institute of Cytology and Genetics, Siberian Branch, Russian Academy of Sciences, Novosibirsk, 630090 Russia *e-mail: [email protected] b
Received April 3, 2020; revised April 16, 2020; accepted April 18, 2020
Abstract—In December 2019, the first cases of pneumonia of unknown etiology were found in Wuhan (China). Later, the pneumonia was associated with a new coronavirus; in February 2020, the World Health Organization (WHO) gave the name COVID-19 to the new disease, while the International Committee on Taxonomy of Viruses (ICTV) gave the name SARS-CoV-2 to the virus causing it. By March 11, 2020, when the virus had spread to 114 countries, the number of diagnosed patients had reached 118 thousand and the number of deaths was 4000, the WHO declared the outbreak of the disease a pandemic. In this review, we summarize the relevant information about the origin and spread of SARS-CoV-2, its epidemiology and diagnostics, and the clinical course and treatment of COVID-19. Keywords: coronavirus, COVID-19, SARS-CoV-2, epidemiology DOI: 10.3103/S0891416820020044
navirus-monitor.ru), and on a web aggregator supported by Johns Hopkins University, United States (https:// gisanddata.maps.arcgis.com/apps/opsdashboard/index. html#/bda7594740fd40299423467b48e9ecf6).
ORIGIN AND SPREAD OF COVID-19 In December 2019, cases of pneumonia of unknown etiology appeared in China in Hubei province. Almost all the first cases of the disease were found in individuals working in the market or visiting the seafood market in Wuhan. In January 2020, a new coronavirus was detected in patients with pneumonia [1]. In February 2020, the World Health Organization (WHO) gave the name COVID-19 to the new disease, while the International Committee on Taxonomy of Viruses (ICTV) gave the name SARS-CoV-2 to the virus. By February 15, 2020, the number of individuals who had been diagnosed with COVID-19 in China exceeded 50 thousand, while a few (less than 50, except for Singapore and the cruise ship Diamond Princess) cases of the disease were observed in other countries [2]. Despite the quarantine measures that were taken, the disease spread rapidly. On March 11, 2020, the WHO declared the outbreak of the disease to be a pandemic [3]; by this time, the virus had spread to 114 countries, with the number of diagnosed patients having reached 118 thousand and the number of deaths 4 thousand [4]. When this article was written (April 16, 2020), the pandemic spanned 213 countries; in the world, there are more than 2 million cases and more than 134 thousand deaths from COVID-19 [5]. In many countries, the number of cases and deaths are growing exponentially. The current statistics is available on the WHO website (https://www.who.int/ emergencies/diseases/novel-coronavirus-2019/situation-reports/), on a Russian site (https://www.coro-
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