The role of income disparities on survival in metastatic clear cell renal cell carcinoma in the targeted therapy era
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ORIGINAL PAPER
The role of income disparities on survival in metastatic clear cell renal cell carcinoma in the targeted therapy era Yawen Zheng1,2 · Yilun Sun3 · Hongyan Yang1 · Jie Liu1 · Ligang Xing2 · Yuping Sun1 Received: 14 January 2020 / Accepted: 23 July 2020 © Springer-Verlag GmbH Germany, part of Springer Nature 2020
Abstract Purpose The influence of socioeconomic status on metastatic clear cell renal cell carcinoma (RCC) in the target therapy era is still unknown. This study aimed to assess the role of income disparities on prognosis of mRCC in the targeted therapy era. Patients and methods Data of patients with mRCC were extracted from the Surveillance, Epidemiology, and End Results (SEER) database. Median household income (MHI) was used to represent patients’ socioeconomic status, and its role on overall survival (OS) and cancer-specific survival (CSS) was evaluated. Results A total of 3791 patients with clear cell mRCC diagnosed between 2010 and 2015 were enrolled in cohort one. There was an obvious imbalance of race and insurance status in patients with difference MHI. Compared with patients in the poorest quartile 1 (Q1), those in the wealthiest Q4 had a 4-month prolonged OS (P
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