Validation of a patient satisfaction questionnaire for anemia treatment, the PSQ-An
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Validation of a patient satisfaction questionnaire for anemia treatment, the PSQ-An Robert J Nordyke*1,2, Chih-Hung Chang3, Chiun-Fang Chiou1, Joel F Wallace4, Bin Yao4 and Lee S Schwartzberg5 Address: 1Cerner Health Insights, 9100 Wilshire Blvd. Ste. 655E, Beverly Hills, CA 90290, USA, 2UCLA School of Public Health, Los Angeles, CA, USA, 3Northwestern University Feinberg School of Medicine, Chicago, IL, USA, 4Amgen, Thousand Oaks, CA, USA and 5The West Clinic, Memphis, TN, USA Email: Robert J Nordyke* - [email protected]; Chih-Hung Chang - [email protected]; Chiun-Fang Chiou - [email protected]; Joel F Wallace - [email protected]; Bin Yao - [email protected]; Lee S Schwartzberg - [email protected] * Corresponding author
Published: 03 May 2006 Health and Quality of Life Outcomes 2006, 4:28
doi:10.1186/1477-7525-4-28
Received: 13 December 2005 Accepted: 03 May 2006
This article is available from: http://www.hqlo.com/content/4/1/28 © 2006 Nordyke et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract Background: Treating anemia associated with chemotherapy and many cancers is often necessary. However, patient satisfaction with anemia treatment is limited by the lack of validated instruments. We developed and validated a new treatment-specific patient satisfaction instrument: the Patient Satisfaction Questionnaire for Anemia Treatment (PSQ-An). Treatment burden and overall satisfaction scales were designed for ease of use in clinical practice. Methods: 312 cancer patients (141 breast, 69 gynecological, and 102 non-small cell lung) were targeted to complete the PSQ-An at 4 week intervals. Data from weeks 5 and 9 were analyzed. Patients also completed the MOS SF-36 Global Health assessment and questions concerning resources devoted to anemia treatment. Item reduction used endorsement rates, floor/ceiling effects, and item-item correlations. Factor analysis identified meaningful subscales. Test-retest reliability was assessed. Construct validity was tested, using Pearson's correlations, by comparing subscale scores to Global Health, hemoglobin levels, and resources devoted to anemia treatment. Results: The overall response rate was 92.9% (264/284) at week 5. Most (84.2%) of the patients were female, and the mean (SD) age was 60.2 (± 11.8) years. Two distinct subscales were identified measuring treatment burden (7 items) and overall satisfaction (2 items). Test-retest reliability was examined (ICC: 0.45–0.67); both were internally consistent (alpha = 0.83). Both subscales exhibited convergent and divergent validity with independent measures of health. ANOVA results indicated that the PSQ-An Satisfaction subscale discriminated between 5 levels of MOS SF-36 Global Health (P = 0.006). Conclusion: The PSQ-An is a validated,
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