Quality of Life in Liver Cirrhosis
Liver cirrhosis is a chronic condition imposing a considerable burden on patients, families, health care, and society. Assessment of health-related quality of life (QOL) is particularly important for these patients in view of the paucity of therapies subs
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Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2240
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Assessment of Quality of Life in Patients with Liver Cirrhosis . . . . . . . . . . . . . . . . . . 2241
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Liver Cirrhosis and Health-Related QOL . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2242
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Etiology of Liver Cirrhosis and Health-Related QOL . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2242
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The Impact of Severity and Complications of Liver Cirrhosis on Health-Related QOL . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2243 5.1 Hepatic Encephalopathy and Impairment of Health-Related QOL . . . . . . . . . . . . . . . . 2244 5.2 Minimal Hepatic Encephalopathy and Fitness to Drive . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2246 6 The Impact of Cirrhosis-Related Symptoms on Health-Related QOL . . . . . . . . . . . 2247 6.1 Fatigue and Impairment of Health-Related QOL . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2247 6.2 Gastrointestinal Symptoms and Impairment of Health-Related QOL . . . . . . . . . . . . . 2249 7
The Impact of Psychological Distress on Health-Related QOL in Liver Cirrhosis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2249
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The Impact of Medical Interventions and Liver Transplantation on Health-Related QOL in Liver Cirrhosis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2250 8.1 Transjugular Intrahepatic Portosystemic Shunt (TIPS) and Health-Related QOL . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2251 8.2 Liver Transplantation and Health-Related QOL . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2251 9
Assessment of Utilities and Health-Related QOL in Liver Cirrhosis . . . . . . . . . . . . 2251
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Conclusions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2252 Summary Points . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2252
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Springer Science+Business Media LLC 2010 (USA)
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Quality of Life in Liver Cirrhosis
Abstract: Liver cirrhosis is a chronic condition imposing a considerable burden on patients, families, health care, and society. Assessment of health-related quality of life (QOL) is particularly important for these patients in view of the paucity of therapies substantially improving their survival except for liver transplantation. To date several investigators employing numerous generic and disease-specific QOL measurement instruments have reported poor QOL in these patients irrespective of the etiology of liver disease. Apart from the
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