Quality of Life in Systemic Sclerosis
Systemic sclerosis (SSc) is a connective-tissue disease characterized by excessive collagen deposition and by vascular hyper-reactivity and obliterative microvascular phenomena. In addition to diminishing life expectancy, SSc is responsible for skin, ten
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Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3824
2 Measuring Health Related Quality of Life in SSc Patients . . . . . . . . . . . . . . . . . . . . . . 3826 2.1 SF-36 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3827 2.2 WHODAS II . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3828 3
Measuring Health Related Quality of Life in SSc Patients with Interstitial Lung Disease . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3830
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Measuring Disability and Participation Restrictions . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3830
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Evaluation of Patient Priorities . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3831
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Comparison of Health Related Quality of Life in SSc Patients and in Patients with Other Conditions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3831
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Utilizations of the Methods for Examining Other Diseases and Conditions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3833
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Conclusion . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3833 Summary Points . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3833
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Springer Science+Business Media LLC 2010 (USA)
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Quality of Life in Systemic Sclerosis
Abstract: > Systemic sclerosis (SSc) is a connective-tissue disease characterized by excessive collagen deposition and by vascular hyper-reactivity and obliterative microvascular phenomena. In addition to diminishing life expectancy, SSc is responsible for skin, tendon, joint, and vessel damage, which leads to disability, handicap, and worsening of quality of life. Health related quality of life can be measured in systemic sclerosis patients by using the Medical Outcomes Study 36-Item Short-Form Health Survey and/or the World Health Organization Disability Assessment Schedule II. Health related quality of life has been reported to be compromised in patients with systemic sclerosis. Not surprisingly, health related quality of life, when measured using the 36-Item ShortForm Health Survey, has been reported to be compromised in patients with systemic sclerosis, and the use of the physical component score of the 36-Item Short-Form Health Survey has been shown to discriminate between patients with limited cutaneous SSc and those with diffuse systemic sclerosis. However, the relevance of using the two aggregate scores, phys
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