Rabies
Rabies is an ancient disease and a fearsome one. Although it may not have the economic or public health importance of some other infectious diseases, few are so well known or carry the same emotional impact. Mainly transmitted by the bite of an enraged an
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Yechiel Becker, Series Editor Julia Hadar, Managing Editor DEVELOPMENTS IN VETERINARY VIROLOGY Payne, L.N. (ed.) Marek's Disease (1985) Bumy, A. and Mammerickx, M. (eds.) Enzootic Bovine Leukosis and Bovine Leukemia Virus (1987) Becker, Y. (ed.) African Swine Fever (1987) De Boer, G.F. (ed.) Avian Leukosis (1987) Liess, B. (ed.) Classical Swine Fever and Related Viral Infections (1988) Darai, G. (ed.) Virus Diseases in Laboratory and Captive Animals (1988) Campbell, 1.B. and Charlton, K.M. (eds.) Rabies (1988) Alexander, D.l. (ed.) Newcastle Disease (1988)
DEVELOPMENTS IN MOLECULAR VIROLOGY Becker, Y. (ed.) Herpesvirus DNA (1981) Becker, Y. (ed.) Replication of Viral and Cellular Genomes (1983) Becker, Y. (ed.) Antiviral Drugs and Interferon: The Molecular Basis of Their Activity (1983) Kohn, A. and Fuchs, P. (eds.) Mechanisms of Viral Pathogenesis from Gene to Pathogen (1983) Becker, Y. (ed.) Recombinant DNA Research and Viruses. Cloning and Expression of Viral Genes (1985) Feitelson, M. Molecular Components of Hepatitis B Virus (1985) Becker, Y. (ed.) Viral Messenger RNA: Transcription, Processing, Splicing and Molecular Structure (1985) Doerfler, W. (ed.) Adenovirus DNA: The Viral Genome and Its Expression (1986) Aloni, Y. (ed.) Molecular Aspects of Papovaviruses (1987)
DEVELOPMENTS IN MEDICAL VIROLOGY Levine, P .H. (ed.) Epstein-Barr Virus and Associated Diseases (1985) Becker, Y. (ed.) Virus Infections and Diabetes Mellitus (1987) De Clercq, E. (ed.) Clinical Use of Antiviral Drugs (1988) Revel, M. (ed.) Clinical Aspects of Interferons (1988)
RABIES
edited by:
James B. Campbell University of Toronto Toronto, Ontario and K.M. Charlton Animal Diseases Research Institute Agriculture Canada Nepean, Canada
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Kluwer Academic Publishers Boston/DordrechtiLondon
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Library of Congress Cataloging-in-Publlcation Data Rabies. (Developments in veterinary virology) Includes bibliographies and index. 1. Rabies-Microbiology. 2. Rabies-Pathogenesis. 3. Rabies virus. 4. Rabies in animals-Preventive inoculation. I. Campbell, James B., 1939II. Charlton, K. M. III. Series. [DNLM: 1. Rabies. 2. Rabies Virus. WC 550 Rll38) QR20l.R3R33 1988 636.089 '6953 88-21524 ISBN-13: 978-1-4612-8985-2 e-ISBN-978-1-4613-1755-5 DOl: 10.1007/978-1-4613-1755-5
Copyright © 1988 by Kluwer Academic Publishers Softcover reprint of the hardcover I st edition 1988 All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, mechanical, photocopying, recording, or otherwise, without the prior written permission of the publisher, Kluwer Academic Publishers, 101 Philip Drive,