Radionuclide Imaging of Cardiovascular Disease
Multiple imaging modalities are clinically available for evaluation of global and regional cardiac function, determination of regional myocardial perfusion, and evaluation of coronary anatomy, including SPECT with CT, PET with CT, multi-detector computed
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Matteo Bauckneht, Flavia Ticconi, Roberta Piva, Riemer H. J. A. Slart, Alberto Nieri, Silvia Morbelli, Paola Anna Erba, Cecilia Marini, H. William Strauss, and Gianmario Sambuceti
Contents 20.1 Introduction
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20.2 Myocardial Perfusion Imaging of Coronary Artery Disease 20.2.1 Pathophysiologic Basis of Myocardial Ischemia 20.2.2 Myocardial Perfusion Imaging: Clinical Indications 20.2.3 MPI: Patient Preparation and General Information 20.2.4 MPI: Stressors Characteristics 20.2.5 SPECT-MPI: Radiopharmaceuticals 20.2.6 PET-MPI: Radiopharmaceuticals 20.2.7 MP Image Interpretation 20.2.8 Multimodality Imaging of Coronary Atherosclerotic Disease
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20.3 Multimodality Imaging in Cardiovascular Infections 20.3.1 Clinical Background on Infections of the Cardiovascular System 20.3.2 Radionuclide Imaging Techniques in Cardiac Infections 20.3.3 Radionuclide Imaging of Prosthetic Valve Endocarditis 20.3.4 Radionuclide Imaging of Native Valve Endocarditis 20.3.5 Radionuclide Imaging of CIED Infections 20.3.6 Radionuclide Imaging of LVAD-Related Infections 20.3.7 Extracardiac Workup of Patients with Infective Endocarditis 20.3.8 Clinical Background on Vascular Prosthetic Infections
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M. Bauckneht Nuclear Medicine, IRCCS Policlinico San Martino, Genoa, Italy F. Ticconi · R. Piva · A. Nieri Nuclear Medicine, Department of Health Sciences, University of Genoa, Genoa, Italy Riemer H. J. A. Slart Biomedical Photonic Imaging Group, University of Twente, Enschede, The Netherlands S. Morbelli · G. Sambuceti (*) Nuclear Medicine, IRCCS Policlinico San Martino, Genoa, Italy Nuclear Medicine, Department of Health Sciences, University of Genoa, Genoa, Italy e-mail: [email protected]
P. A. Erba Regional Center of Nuclear Medicine, Department of Translational Research and Advanced Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy C. Marini Nuclear Medicine, Department of Health Sciences, University of Genoa, Genoa, Italy CNR Institute of Bioimages and Molecular Physiology, Milan, Italy H. W. Strauss Molecular Imaging and Therapy Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA
© Springer Nature Switzerland AG 2019 D. Volterrani et al. (eds.), Nuclear Medicine Textbook, https://doi.org/10.1007/978-3-319-95564-3_20
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M. Bauckneht et al. 20.4 C linical Indications, Technique, and Principles of Noninfectious, Non-atherosclerotic Cardiovascular Diseases 20.4.1 Clinical Background on Myocarditis 20.4.2 Clinical Background on Acute Pericarditis 20.4.3 Clinical Background on Cardiac Sarcoidosis 20.4.4 Clinical Background on Cardiac Amyloidosis
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20.5 Heart Failure
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20.6 Large Vessels Vasculitis
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References
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Learning Objectives
• Define the rationale underlying the use of radionuclide methods in cardiovascular diseases. • Understand the clinical conditions in which nuclear medic
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