Randomized trial of exercise in sedentary middle aged women: effects on quality of life

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Randomized trial of exercise in sedentary middle aged women: effects on quality of life Deborah J Bowen1, Megan D Fesinmeyer1, Yutaka Yasui2, Shelley Tworoger3, Cornelia M Ulrich1, Melinda L Irwin4, Rebecca E Rudolph1,5, Kristin L LaCroix1, Robert R Schwartz6 and Anne McTiernan*1 Address: 1Cancer Prevention, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave N, Seattle WA 98109, USA, 2Department of Public Health Sciences, University of Alberta, 13-106J Clinical Sciences Building, Edmonton, AB, 6G 2G3, Canada, 3Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard University, 181 Longwood Avenue, Boston MA 02115, USA, 4Department of Epidemiology and Public Health, Yale University, PO Box 208034, New Haven CT 06520, USA, 5Health Services Research and Development Center of Excellence, Department of Veterans Affairs, 1100 Olive Way, Suite 1400, Seattle, WA, 98101, USA and 6Department of Internal Medicine, University of Colorado Health Sciences Center, 4200 E. 9th Avenue, Campus Box B-179, Denver CO 80262, USA Email: Deborah J Bowen - [email protected]; Megan D Fesinmeyer - [email protected]; Yutaka Yasui - [email protected]; Shelley Tworoger - [email protected]; Cornelia M Ulrich - [email protected]; Melinda L Irwin - [email protected]; Rebecca E Rudolph - [email protected]; Kristin L LaCroix - [email protected]; Robert R Schwartz - [email protected]; Anne McTiernan* - [email protected] * Corresponding author

Published: 04 October 2006 International Journal of Behavioral Nutrition and Physical Activity 2006, 3:34 5868-3-34

doi:10.1186/1479-

Received: 15 December 2005 Accepted: 04 October 2006

This article is available from: http://www.ijbnpa.org/content/3/1/34 © 2006 Bowen et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract Increasing physical activity is currently considered to be a possible prevention strategy for cancer, obesity, and cardiovascular disease, either alone or in combination with dietary changes. This paper presents results of a randomized trial of moderate-to-vigorous intensity exercise in middle aged, sedentary women; specifically, we report changes in and correlates of quality of life and functional status of this exercise intervention program for both the short (three months) and longer term (12 months). The intervention group showed a significant increase in Mental Health score from baseline to 3 months (p < .01), significantly greater than the change in the control group at 3 months (p < .01). A similar trend among exercisers was observed for the General Health score (p < .01), and this finding was significantly greater than the change in control group at 3 months (p = .01). Change in Social Support – Affection were pred