Rates and Anticoagulation Treatment of Known Atrial Fibrillation in Patients with Acute Ischemic Stroke: A Real-World St
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ORIGINAL RESEARCH
Rates and Anticoagulation Treatment of Known Atrial Fibrillation in Patients with Acute Ischemic Stroke: A Real-World Study Huijie Yuan . Jiaqi An . Qiang Zhang . Xiao Zhang . Man Sun . Tong Fan . Yawen Cheng . Meng Wei . Gary Tse . Xavier Waintraub . Yongxin Li . John D. Day . Fan Gao . Guogang Luo . Guoliang Li
Received: July 1, 2020 Ó Springer Healthcare Ltd., part of Springer Nature 2020
ABSTRACT Introduction: Known atrial fibrillation (AF) rate and appropriate prescription of oral anticoagulants (OACs) in acute ischemic stroke (AIS) patients with AF in China are not as well known as in Western countries. Digital Features This article is published with digital features to facilitate understanding. You can access the digital features on the article’s associated Figshare page. To view digital features for this article go to https://doi. org/10.6084/m9.figshare.12777134. H. Yuan J. An Y. Cheng M. Wei G. Luo (&) Stroke Centre and Department of Neurology, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, China e-mail: [email protected] H. Yuan J. An G. Li (&) Atrial Fibrillation Centre and Department of Cardiovascular Medicine, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, China e-mail: [email protected] Q. Zhang Department of Neurology, Shaanxi Provincial People’s Hospital, Xi’an, China X. Zhang Department of Neurology, Xijing Hospital of Air Force Military Medical University, Xi’an, China M. Sun Department of Neurology, The Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an, China
Methods: Known AF and unknown AF, rate and adequacy of OACs use of AIS patients with AF attending five hospitals from April 2018 to August 2019 in the northwest region of China were investigated. Results: A total of 344 patients were enrolled. Of these, 237 (AF-known group; 237/344, 68.9%) and 107 patients (AF-unknown group; 107/344, 31.1%) were diagnosed with AF before and after AIS during this hospitalization, respectively. In the AF-known group with echocardiography results (178 patients, includT. Fan Department of Neurology, Xi’an Gaoxin Hospital, Xi’an, China G. Tse Xiamen Cardiovascular Hospital, Xiamen University, Xiamen, China X. Waintraub ˆ pital Rhythmology Unit, Cardiology Institute, Ho Universitaire La Pitie´-Salpeˆtrie`re, Paris, France Y. Li Department of Cardiovascular Surgery, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, China J. D. Day Intermountain Medical Center Heart Institute, Murray, UT, United States F. Gao Clinical Research Center, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, China
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ing 103 female and 75 male patients), 154 of overall, 88 of female and 66 of male patients, respectively, were indicated to be taking OACs. However, the actual OACs proportion was much lower [overall (30.5%, 47/154); female (31.8%, 28/88) and male (28.8%, 19/66) patients] than indicated. Only one female patient met the guideline-based criteria for OACs. As for patients diagnosed with massive cer
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