Recent Advances in Retinal Degeneration

Retinal Degenerations is the result of The International Symposium on Retinal Degeneration which has become perhaps the most important research meeting in the field. The topics in this volume explore the etiology, cellular mechanisms, epidemiology, generi

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Advances in Experimental Medicine and Biology Editorial Board: Nathan Back, State University of New York at Buffalo Irun R. Cohen, The Weizmann Institute of Science Abel Lajtha, N.S., Kline Institute for Psychiatric Research John D. Lambris, University of Pennsylvania Rodolfo Paoletti, University of Milan

Recent Volumes in this Series VOLUME 606

BIOACTIVE COMPONENTS OF MILK Edited by Zsuzsanna B˝osze

VOLUME 607

EUKARYOTIC MEMBRANES AND CYTOSKELETON: ORIGINS AND EVOLUTION Edited by Gáspár Jékely

VOLUME 608

BREAST CANCER CHEMOSENSITIVITY Edited by Dihua Yu and Mien-Chie Hung

VOLUME 609

HOT TOPICS IN INFECTION AND IMMUNITY IN CHILDREN IV Edited by Adam Finn and Andrew J. Pollard

VOLUME 610

TARGET THERAPIES IN CANCER Edited by Francesco Colotta and Alberto Mantovani

VOLUME 611

PETIDES FOR YOUTH Edited by Susan Del Valle, Emanuel Escher, and William D. Lubell

VOLUME 612

RELAXIN AND RELATED PETIDES Edited by Alexander I. Agoulnik

VOLUME 613

RECENT ADVANCES IN RETINAL DEGENERATION Edited by Robert E. Anderson, Matthew M. LaVail, and Joe G. Hollyfield

A Continuation Order Plan is available for this series. A continuation order will bring delivery of each new volume immediately upon publication. Volumes are billed only upon actual shipment. For further information please contact the publisher.

Robert E. Anderson · Matthew M. LaVail Joe G. Hollyfield Editors

Recent Advances in Retinal Degeneration

Editors Robert E. Anderson Dean A. McGee Eye Institute University of Oklahoma Health Science Ctr. 608 Stanton L. Young Blvd., DMEI 409 Oklahoma City, OK 73104 USA [email protected]

Matthew M. LaVail Beckman Vision Center UCSF School of Medicine 10 Kirkham Street San Francisco, CA 94143 USA [email protected]

Joe G. Hollyfield Cole Eye Institute The Cleveland Clinic Foundation 9500 Euclid Ave. (i31) Cleveland, OH 44195 [email protected]

The chapter “Characterization of Gene Expression Profiles of Normal Canine Retina and Brain Using a Retinal cDNA Microarray” has been retracted due to plagiarism. A large portion of its contents were copied from another paper.

ISBN: 978-0-387-74902-0

e-ISBN: 978-0-387-74904-4

Library of Congress Control Number: 2007936186 2008 Springer Science+Business Media, LLC All rights reserved. This work may not be translated or copied in whole or in part without the written permission of the publisher (Springer Science+Business Media, LLC., 233 Spring Street, New York, NY10013, USA), except for brief excerpts in connection with reviews or scholarly analysis. Use in connection with any form of information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed is forbidden. The use in this publication of trade names, trademarks, service marks, and similar terms, even if they are not identified as such, is not to be taken as an expression of opinion as to whether or not they are subject to proprietary rights.

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Dedication

Nicola