Recurrent Respiratory Papillomatosis

This volume provides a comprehensive review of recurrent respiratory papillomatosis and an up-to-date understanding of the etiology, pathophysiology, and management of these rare tumors caused by the human papillomavirus (HPV). The text covers the potenti

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Recurrent Respiratory Papillomatosis

Paolo Campisi Editor

Recurrent Respiratory Papillomatosis

Editor Paolo Campisi Department of Otolaryngology - Head and Neck Surgery University of Toronto Toronto, ON Canada

ISBN 978-3-319-63822-5    ISBN 978-3-319-63823-2 (eBook) https://doi.org/10.1007/978-3-319-63823-2 Library of Congress Control Number: 2017956567 © Springer International Publishing AG 2018 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer International Publishing AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland

This collaborative work is dedicated to the children and adults that courageously live with recurrent respiratory papillomatosis. Together we will advocate for the prevention of RRP and strive for the development of novel, effective treatments.

Foreword

It is with great pleasure and honour that I write the foreword to this most impressive book on RRP edited by a trusted friend and colleague, Dr. Paolo Campisi. As a retired paediatric otolaryngologist/head and neck surgeon, I dealt first-hand with many patients suffering from this disease. Throughout my education as a resident and during my career for more than 30 years, I witnessed the pain, suffering and disruption of quality of life of child, parent and family alike. In my early years, I sensed frustration amongst all the health-care providers, myself included, and researchers with the lack of understanding and effective treatment options available for these children. To put it bluntly, we were poorly equipped and lacking on all fronts. With pure motivation to relieve pain and suffering, we all wanted to do better, and so we did. Course crude debulking techniques performed via direct laryngoscopy were replaced with innovative microsurg