Regulation of Sertoli Cell and Germ Cell Differentation
Unwanted childlessness affects approximately one in six couples worldwide. - though the exact proportion of the predominant cause of the problem remains controversial, according to the World Health Organization (WHO), in nearly 40% of cases the cause can
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Editors F. F. Beck, Melbourne · B. Christ, Freiburg F. Clascá, Madrid · D. E. Haines, Jackson H.-W. Korf, Frankfurt · W. Kummer, Giessen E. Marani, Leiden · R. Putz, München Y. Sano, Kyoto · T. H. Schiebler, Würzburg K. Zilles, Düsseldorf
R. Brehm · K. Steger
Regulation of Sertoli Cell and Germ Cell Differentation With 26 Figures
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Dr. Ralph Brehm Institut für Veterinär-Anatomie, Histologie und Embryologie Justus-Liebig Universtät Frankfurter Str. 98 35392 Giessen Germany e-mail: [email protected]
PD Dr. Klaus Steger Klinik und Poliklinik für Urologie und Kinderurologie Justus-Liebig Universtät Rudolf-Buchheim-Str. 7 35385 Giessen Germany e-mail: [email protected]
Library of Congress Catalog Number 2005926766 ISSN 0301-5556 ISBN-10 3-540-25750-0 Springer Berlin Heidelberg New York ISBN-13 978-3-540-25750-9 Springer Berlin Heidelberg New York
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Preface
Unwanted childlessness affects approximately one in six couples worldwide. Although the exact proportion of the predominant cause of the problem remains controversial, according to the World Health Organization (WHO), in nearly 40% of cases the cause can be attributed to the female, in 20% to the male, in 25% to both, and in 15% the cause remains unknown. Based on these figures, the incidence of male factor infertility in the general population is approximately 7%. The majority of these men, approximately 30%, experience irreversible idiopathic infertility and cannot father children without some form of medical intervention. Male factor
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