Renal Cancer Contemporary Management
This fully updated second edition provides a comprehensive, state-of-the-art review of renal cancer, and will serve as a guide for urology residents, clinicians, surgeons, and researchers with an interest in renal cell carcinoma. The title reviews the lat
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Renal Cancer
John A. Libertino • Jason R. Gee Editors
Renal Cancer Contemporary Management Second Edition
Editors John A. Libertino Professor of Urology Tufts University School of Medicine Boston, MA USA Chairman Department of Urology MGH Cancer Center Emerson Hospital Concord, MA USA
Jason R. Gee Associate Professor of Urology Tufts University School of Medicine Boston, MA USA Department of Urology MGH Cancer Center Emerson Hospital Concord, MA USA
ISBN 978-3-030-24377-7 ISBN 978-3-030-24378-4 (eBook) https://doi.org/10.1007/978-3-030-24378-4 © Springer Nature Switzerland AG 2020 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, expressed or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Switzerland AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland
Dedicated to Dr. Harris Berman, M.D., Dean of Tufts University School of Medicine A great Leader in medical education and healthcare delivery
Contents
1 Epidemiology, Screening, and Clinical Staging���������������������������� 1 Sana N. Siddiqui, Christopher R. Haas, and James M. McKiernan Introduction to Epidemiology���������������������������������������������������������� 1 Incidence and Mortality Rates over Time���������������������������������������� 1 Demographic Factors in Renal Cell Carcinoma������������������������������ 3 Risk Factors in the Development of RCC���������������������������������������� 3 Smoking �������������������������������������������������������������������������������������� 3 Diet���������������������������������������������������������������������������������������������� 4 Obesity ���������������������������������������������������������������������������������������� 4 Hypertension�������������������������������������������������������������������������������� 4 Chronic Renal D