Retrospective study of the treatment of port-wine stains with 595-nm pulsed dye laser in 261 Chinese patients
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ORIGINAL ARTICLE
Retrospective study of the treatment of port-wine stains with 595-nm pulsed dye laser in 261 Chinese patients Dong Li 1 & Bin Chen 1 & Hao Zhang 1 & Yuan Yuan 1 & Wenxin Fan 2 & Zhaoxia Ying 2 Received: 20 December 2019 / Accepted: 29 March 2020 # Springer-Verlag London Ltd., part of Springer Nature 2020
Abstract Pulsed dye laser (PDL) at the wavelength of 595 nm is the common choice for the treatment of port-wine stains (PWSs). In this study, the efficacy of 595-nm PDL in treatment of PWSs in Chinese patients was investigated. A follow-up visit was performed on 261 Fitzpatrick skin type II–III Chinese patients with PWS who received more than two treatments with 595-nm PDL. Based on cosmetic improvement, treatment response was graded as follows: complete, if color blanching was > 90%; significant, if color blanching was 60–90%; moderate, if color blanching was 30–60%; and poor, if color blanching was < 30%. The efficacy of laser treatment on patients of different treatment numbers, ages, lesion locations, lesion colors, extents of hypertrophy, and laser pulse durations was evaluated. All patients improved following an average of almost 4 to 5 laser treatments. The earlier the intervention, the better the efficacy was. Lesions on cheek, neck, and forehead were better than that those on oral, eye periorbital, and nose areas. The purple group had a more excellent clearance, i.e., complete and significant clearance rate (53.6%), than the red group (36.1%). Treatment effect became worse as the extent of lesion hypertrophy increased. PWS lesions treated with short pulse durations of 0.45, 1.5, and 3 ms had better clearance (complete and significant clearance) rate of 56.5% than those treated with pulse durations of 6 ms or longer (34.8%). Pulsed dye laser with 595-nm laser equipped with dynamic cooling device is an effective option for the treatment of PWS in Chinese patients. Younger patients with lateral face position, larger vessel size (deeper color), and lesser hypertrophy received better clinical effect than the others. Treatment with short pulse duration of less than 3 ms for 4 to 5 times was recommended to treat PWS. Keywords Port-wine stain . Laser surgery . Clinic review . Chinese patients
Introduction Port-wine stains (PWSs) are a congenital microvascular malformation consisting of ectasia of capillaries and venules of the skin, occurring in 0.3% to 0.5% of newborns [1, 2]. PWS commonly occurs in the face and neck, presents flat and pink at birth, and becomes darker and thicker with age, seriously influencing the mental and physical health of patients. PWS
* Bin Chen [email protected] * Zhaoxia Ying [email protected] 1
State Key Laboratory of Multiphase Flow in Power Engineering, Xi’an Jiaotong University, Xi’an 710049, Shaanxi, China
2
Department of Dermatology, The Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an 710004, Shaanxi, China
persists throughout the lifetime of the patient and progresses with aging, particularly showing raised, irregularly surface, and de
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