Risk factors for decompressive craniectomy after endovascular treatment in acute ischemic stroke
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ORIGINAL ARTICLE
Risk factors for decompressive craniectomy after endovascular treatment in acute ischemic stroke Guoyi Peng 1 & Chuming Huang 2 & Weiqiang Chen 3 & Chukai Xu 2 & Mingfa Liu 1 & Haixiong Xu 1 & Chuwei Cai 1,4 Received: 23 April 2019 / Revised: 7 August 2019 / Accepted: 20 August 2019 # Springer-Verlag GmbH Germany, part of Springer Nature 2019
Abstract Endovascular treatment (EVT) is safe and effective for acute ischemic stroke (AIS) caused by large artery occlusion in the anterior circulation. However, some patients require decompressive craniectomy (DC), despite having undergone a timely EVT. This study aimed to evaluate the risk factors for subsequent DC after EVT. This retrospective cohort study comprised 138 patients who received EVT between April 2015 and June 2019 at our center. The need for subsequent DC was defined as cerebral edema or/and hemorrhagic transformation caused by large ischemic infarction, with a ≥ 5-mm midline shift and clinical deterioration after EVT. The relationship between risk factors and DC after EVT was assessed via univariate and multivariable logistic regression. Thirty (21.7%) patients required DC. These patients tended to have atrial fibrillation (P = 0.037), sedation (P = 0.049), mechanical ventilation (P = 0.008), poorer collateral circulation (P = 0.003), a higher baseline National Institutes of Health Stroke Scale (NIHSS) score (P < 0.001), heavier thrombus burden (P < 0.001), a lower baseline Alberta Stroke Program Early Computed Tomography Score (ASPECTS) (P < 0.001), and unsuccessful recanalization (P < 0.001). In the multivariate analysis, higher baseline NIHSS score [odds ratio (OR), 1.17; 95% confidence interval (CI), 1.03–1.32], heavier thrombus burden [OR, 1.35; 95% CI, 1.02–1.79], baseline ASPECTS ≤ 8 [OR, 7.41; 95% CI, 2.43–22.66], and unsuccessful recanalization [OR, 7.49; 95% CI, 2.13–26.36] were independent risk factors for DC after EVT. DC remains an essential treatment for some AIS patients after EVT, especially those with higher baseline NIHSS scores, heavier thrombus burden, baseline ASPECTS ≤ 8, and unsuccessful recanalization. Keywords Artery occlusion . Thrombectomy . Stroke . Malignant MCA infarction . Decompressive craniectomy
Introduction * Haixiong Xu [email protected] * Chuwei Cai [email protected] 1
Department of Neurosurgery, Shantou Central Hospital, Affiliated Shantou Hospital of Sun Yat-Sen University, 114 Waima Road, Shantou 515041, Guangdong, China
2
Department of Neurology, Shantou Central Hospital, Affiliated Shantou Hospital of Sun Yat-Sen University, 114 Waima Road, Shantou 515041, Guangdong, China
3
Department of Neurosurgery, First Affiliated Hospital, Shantou University Medical College, 57 Changping Road, Shantou 515041, Guangdong, China
4
Department of Intervention Neuroradiology, Shantou Central Hospital, Affiliated Shantou Hospital of Sun Yat-Sen University, 114 Waima Road, Shantou 515041, Guangdong, China
Intracranial carotid artery (ICA) and proximal middle cerebral artery (MCA) occlusions often result i
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