Role of Exosomes in Biological Communication Systems
This book reviews the role of exosomes and extracellular vesicles in both normal and pathological conditions. It first explains isolation methods for exosomes, and analyzes their fine structure and biological functions. Further, it highlights exosomes’ ro
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e of Exosomes in Biological Communication Systems
Role of Exosomes in Biological Communication Systems
Faisal A. Alzahrani • Islam M. Saadeldin Editors
Role of Exosomes in Biological Communication Systems
Editors Faisal A. Alzahrani Department of Biochemistry, ESC Research Unit, Faculty of Science King Fahd Medical Research Center King Abdulaziz University Jeddah, Saudi Arabia
Islam M. Saadeldin Department of Animal Production King Saud University Riyadh, Saudi Arabia
ISBN 978-981-15-6598-4 ISBN 978-981-15-6599-1 https://doi.org/10.1007/978-981-15-6599-1
(eBook)
# Springer Nature Singapore Pte Ltd. 2021 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, expressed or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Singapore Pte Ltd. The registered company address is: 152 Beach Road, #21-01/04 Gateway East, Singapore 189721, Singapore
Preface
Exosomes as membrane-bound extracellular vesicles (EVs) are an active area of research and, known as universal minute nanosized vehicles, can be released from all cells in all prokaryotes and eukaryotes to transfer genetic instructions between cells. EVs deliver proteins, mRNAs, miRNAs, lipids, metabolites, and enzymes to alter cell functions on the physiological or pathological levels. There are tremendous increase and thousands of publications related to the isolation, characterization, and functional analysis of EVs. The physiological purpose of generating EVs remains largely unknown and needs investigation. One speculated role is that EVs likely remove excess and/or unnecessary constituents from cells to maintain cellular homeostasis. Recent studies reviewed here also indicate a functional, targeted, mechanism-driven accumulation of specific cellular components in EVs, suggesting that they have a role in regulating intercellular communication. More attention has been given to the regenerative capa
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