SARS-COV-2 infection during pregnancy, a risk factor for eclampsia or neurological manifestations of COVID-19? Case repo
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(2020) 20:587
CASE REPORT
Open Access
SARS-COV-2 infection during pregnancy, a risk factor for eclampsia or neurological manifestations of COVID-19? Case report Alejandro Garcia Rodriguez1†, Sergio Marcos Contreras1*† , Santiago Manuel Fernandez Manovel1, Jose Miguel Marcos Vidal1, Fernando Diez Buron1, Camino Fernandez Fernandez2 and Maria del Carmen Riveira Gonzalez3
Abstract Background: There are no published cases of tonic-clonic seizures and posterior bilateral blindness during pregnancy and Severe Acute Respiratory Syndrome (SARS) Coronavirus (COV) 2 (SARS-COV-2) infection. We do not just face new and unknown manifestations, but also how different patient groups are affected by SARS-COV-2 infection, such as pregnant women. Coronavirus Disease 2019 (COVID-19), preeclampsia, eclampsia and posterior reversible leukoencephalopathy share endothelium damage and similar pathophysiology. Case presentation: A 35-year-old pregnant woman was admitted for tonic-clonic seizures and SARS-COV-2 infection. She had a normal pregnancy control and no other symptoms before tonic-clonic seizures development. After a Caesarean section (C-section) she developed high blood pressure, and we initiated antihypertensive treatment with labetalol, amlodipine and captopril. Few hours later she developed symptoms of cortical blindness that resolved in 72 h with normal brain computed tomography (CT) angiography. Conclusion: The authors conclude that SARS COV-2 infection could promote brain endothelial damage and facilitate neurological complications during pregnancy. Keywords: COVID-19, Case-report, Pregnancy, Preeclampsia, Neurological manifestations
Background The vast majority of patients affected by SARS-COV-2 infection present flu-like symptoms [1, 2]. However, as the pandemic evolves, a broader, diverse and unknown spectrum of symptoms can be observed. An increasing number of patients with neurological symptoms have been reported [3–6]. These manifestations can go from mild and common symptoms such as anosmia or ageusia, to severe ones and less common such as a
cerebrovascular accident [3–6]. Symptoms of extrapulmonary disease could be explained by the damage of the endothelial tissue caused by the virus [7]. With this new virus, we do not just face new and unknown manifestations, but also how different patient groups are affected by SARS-COV-2 infection, such as pregnant women. That is the reason why we present a case report of a pregnant woman infected with SARSCOV-2 who showed seizures and sudden blindness.
* Correspondence: [email protected] † Alejandro Garcia Rodriguez and Sergio Marcos Contreras contributed equally to this work. 1 Department of Anaesthesiology and Critical Care, University Complex Hospital of Leon, 24071 City Leon, Spain Full list of author information is available at the end of the article
Case presentation We describe 35-year-old pregnant women with just hypothyroidism treated with thyroxin 88 μg every 24 h as personal background and optimal blood pressure control
© The Author(s). 2020 Open Access T
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