Self-administration and interviewer-administration of the German Chronic Respiratory Questionnaire: instrument developme

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Self-administration and interviewer-administration of the German Chronic Respiratory Questionnaire: instrument development and assessment of validity and reliability in two randomised studies Milo A Puhan*1, Michaela Behnke2, Martin Frey3, Thomas Grueter3, Otto Brandli4, Alfred Lichtenschopf5, Gordon H Guyatt6 and Holger J Schunemann6,7 Address: 1Horten Centre, University Hospital of Zurich, Postfach Nord CH-8091 Zurich, Switzerland, 2Ordinariat und Institut für Arbeitsmedizin, University of Hamburg, Germany, 3Klinik Barmelweid, Barmelweid, Switzerland, 4Zuercher Hoehenklinik Wald, Faltigberg-Wald, Switzerland, 5Rehabilitationszentrum, Weyer/Enns, Austria, 6Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada and 7Departments of Medicine and of Social & Preventive Medicine, University at Buffalo, New York, USA Email: Milo A Puhan* - [email protected]; Michaela Behnke - [email protected]; Martin Frey - [email protected]; Thomas Grueter - [email protected]; Otto Brandli - [email protected]; Alfred Lichtenschopf - [email protected]; Gordon H Guyatt - [email protected]; Holger J Schunemann - [email protected] * Corresponding author

Published: 08 January 2004 Health and Quality of Life Outcomes 2004, 2:1

Received: 18 November 2003 Accepted: 08 January 2004

This article is available from: http://www.hqlo.com/content/2/1/1 © 2004 Puhan et al; licensee BioMed Central Ltd. This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original URL.

COPDHealth Related Quality of LifeChronic Respiratory QuestionnaireStandardisationSelf-Administration

Abstract Background: Assessment of health-related quality of life (HRQL) is important in patients with chronic obstructive pulmonary disease (COPD). Despite the high prevalence of COPD in Germany, Switzerland and Austria there is no validated disease-specific instrument available. The objective of this study was to translate the Chronic Respiratory Questionnaire (CRQ), one of the most widely used respiratory HRQL questionnaires, into German, develop an interviewer- and selfadministered version including both standardised and individualised dyspnoea questions, and validate these versions in two randomised studies. Methods: We recruited three groups of patients with COPD in Switzerland, Germany and Austria. The 44 patients of the first group completed the CRQ during pilot testing to adapt the CRQ to German-speaking patients. We then recruited 80 patients participating in pulmonary rehabilitation programs to assess internal consistency reliability and cross-sectional validity of the CRQ. The third group consisted of 38 patients with stable COPD without an intervention to assess test-retest reliability. To compare the interviewer- and self-administered versions, we randomised patients in groups 2 and 3 to the interviewer- or self-administered CRQ. Patients c