Senolytics in Disease, Ageing and Longevity
This book offers comprehensive information on the new and rapidly evolving science of identifying and targeting senescent cells, and on the exciting prospect of new diagnostic and therapeutic opportunities for stopping, and even reversing, the progression
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Daniel Muñoz-Espin Marco Demaria Editors
Senolytics in Disease, Ageing and Longevity
Healthy Ageing and Longevity Volume 11
Series Editor Suresh I.S. Rattan, Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark
Rapidly changing demographics worldwide towards increased proportion of the elderly in the population and increased life-expectancy have brought the issues, such as “why we grow old”, “how we grow old”, “how long can we live”, “how to maintain health”, “how to prevent and treat diseases in old age”, “what are the future perspectives for healthy ageing and longevity” and so on, in the centre stage of scientific, social, political, and economic arena. Although the descriptive aspects of ageing are now well established at the level of species, populations, individuals, and within an individual at the tissue, cell and molecular levels, the implications of such detailed understanding with respect to the aim of achieving healthy ageing and longevity are ever-changing and challenging issues. This continuing success of gerontology, and especially of biogerontology, is attracting the attention of both the well established academicians and the younger generation of students and researchers in biology, medicine, bioinformatics, bioeconomy, sports science, and nutritional sciences, along with sociologists, psychologists, politicians, public health experts, and health-care industry including cosmeceutical-, food-, and lifestyle-industry. Books in this series will cover the topics related to the issues of healthy ageing and longevity. This series will provide not only the exhaustive reviews of the established body of knowledge, but also will give a critical evaluation of the ongoing research and development with respect to theoretical and evidence-based practical and ethical aspects of interventions towards maintaining, recovering and enhancing health and longevity.
More information about this series at http://www.springer.com/series/13277
Daniel Muñoz-Espin Marco Demaria •
Editors
Senolytics in Disease, Ageing and Longevity
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Editors Daniel Muñoz-Espin CRUK Cambridge Centre Early Detection Programme, Department of Oncology Hutchison/MRC Research Centre University of Cambridge Cambridge, UK
Marco Demaria European Research Institute for the Biology of Aging (ERIBA) University Medical Center Groningen Groningen, The Netherlands
ISSN 2199-9007 ISSN 2199-9015 (electronic) Healthy Ageing and Longevity ISBN 978-3-030-44902-5 ISBN 978-3-030-44903-2 (eBook) https://doi.org/10.1007/978-3-030-44903-2 © Springer Nature Switzerland AG 2020 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter develo
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