Serum inflammatory and oxidative stress biomarkers levels are associated with pain intensity, pressure pain threshold an
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BMC Research Notes Open Access
RESEARCH NOTE
Serum inflammatory and oxidative stress biomarkers levels are associated with pain intensity, pressure pain threshold and quality of life in myofascial pain syndrome Seyed Kazem Shakouri1, Neda Dolatkhah1,4* , Sepideh Omidbakhsh2, Alireza Pishgahi1 and Maryam Hashemian3
Abstract Objectives: We aimed to determine the serum concentrations of some inflammatory and oxidative stress biomarkers in relation with pain intensity and quality of life in patients with myofascial pain syndrome (MPS) compared to healthy controls. This study is a case–control study. The participants were selected from MPS patients who referred to rehabilitation outpatient clinics of the Tabriz University of Medical Sciences, Iran. Results: Serum hs-CRP (4.68 ± 4.36 vs. 2.92 ± 4.55 g/mlµ respectively, p = 0.011), phospholipase A2 (PLA2) (6.81 ± 2.22 vs. 4.73 ± 2.97 pg/ml respectively, p 0.001
6.81 ± 2.22
4.73 ± 2.97
> 0.001
PF
68.67 ± 2.631
75.89 ± 18.95
0.057
RP
34.44 ± 42.40
60.00 ± 42.44
0.004
RE
37.02 ± 41.57
59.98 ± 41.19
0.010
EF
55.50 ± 18.82
62.88 ± 20.35
0.077
EW
61.51 ± 16.87
67.75 ± 17.42
0.073
SF
62.55 ± 24.57
72.50 ± 24.65
0.033
P
48.5 ± 20.91
79.27 ± 28.38
0.028
GH
51.81 ± 20.91
63.13 ± 20.64
0.011
PH
202.97 ± 85.09
278.30 ± 88.36
0.001
MH
213.44 ± 79.18
264.61 ± 65.87
0.001
SOD (U/ml) PLA2 (pg/ml)
0.011
Values are means ± SD CRP C-reactive protein, EF energy/fatigue, EW emotional wellbeing, GH general health, hs-CRP high-sensitive, MDA malondialdehyde, MH mental health, P pain, PF physical function, PH physical health, PLA phospholipase A2, RE role limitation due to emotional problems, RP role limitation due to physical health, SF social function, SOD superoxide dismutase, TACtotal antioxidant capacity a
Significantly different at p
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