Side Effects of Medical Cancer Therapy Prevention and Treatment
This is the second edition of a well-received book that reflects the state of the art in cancer medical therapies and their side-effects, including immunotherapy and chemotherapeutic drugs. All chapters have been fully updated to include all the latest &n
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Side Effects of Medical Cancer Therapy
Mario A. Dicato • Eric Van Cutsem Editors
Side Effects of Medical Cancer Therapy Prevention and Treatment Second Edition
Editors Mario A. Dicato Department of Hematology-Oncology Centre Hospitalier de Luxembourg Luxembourg Luxembourg
Eric Van Cutsem Leuven Cancer Institute University Hospitals Leuven Leuven Belgium
ISBN 978-3-319-70252-0 ISBN 978-3-319-70253-7 (eBook) https://doi.org/10.1007/978-3-319-70253-7 Library of Congress Control Number: 2018940897 1st edition: © Springer-Verlag London 2013 2nd edition: © Springer International Publishing AG, part of Springer Nature 2018 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Printed on acid-free paper This Springer imprint is published by the registered company Springer International Publishing AG part of Springer Nature. The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland
Preface to the First Edition
The reason for publishing a book on side effects of drugs used in oncology is the fact that numerous new drugs, mostly classified as “targeted therapy,” have different and very varied spectra of side effects. As standard chemotherapy drugs have not changed much over the years in their adverse effect profiles, oncologists are usually very familiar with these problems, especially because over the past 20 years only a few new chemotherapeutic drugs have been marketed. Another aspect of oncology that has changed over the past two decades is the fact that with the increase in life expectancy, the median age at diagnosis of cancer has increased and is presently around 70 years. Therefore, comorbidities have become routine in oncological services, and many patients are being treated with multiple medications for other pathologies, which multiplies drug interactions and compliance problems. Targeted drugs have flooded the oncological lit
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