Skeletal Dysplasia
Skeletal dysplasias are a heterogeneous group of more than 400 disorders that affect bone and cartilage growth. Skeletal dysplasias occur at a rate of 1 in 4000–5000 births. Prenatal diagnosis is clinically important because most of them develop from the
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Hideaki Masuzaki Editor
Fetal Morph Functional Diagnosis
Comprehensive Gynecology and Obstetrics Series Editors Ikuo Konishi National Kyoto Medical Center Kyoto Japan Hidetaka Katabuchi Department of Obstetrics and Gynecology Kumamoto University Kumamoto Japan
This series presents the current and future perspectives of medical science in gynecology and obstetrics. The authors fully describe the current understanding of a disease including clinical features, imaging, pathology, and molecular biology, and also include the historical aspects and theories for exploring the etiology of the disease. Also, recent developments in diagnostic strategy, medical treatment, surgery, radiotherapy, prevention, and better health-care methods are clearly shown. Thus, each volume in the series focuses on the scientific basis for the pathogenesis of a disease and provides clinical applications that make it possible to offer personalized treatment for each patient. Over the past 20 years, physicians have been working to develop a standard treatment and publish clinical guidelines for a disease based on epidemiological evidence, mainly through the use of randomized clinical trials and meta-analyses. Recently, however, comprehensive genomic and genetic analyses have revealed the differences and variations in biological characteristics even among patients with the same diagnosis and have been focusing on personalized therapy. Now all physicians and patients are entering a new world of “precision medicine” through the use of genomic evidence. We are confident that readers will greatly benefit from the contents of the series with its purview of the exciting and promising future of gynecology and obstetrics. More information about this series at http://www.springer.com/series/13621
Hideaki Masuzaki Editor
Fetal Morph Functional Diagnosis
Editor Hideaki Masuzaki Nagasaki University Nagasaki Japan
ISSN 2364-1932 ISSN 2364-219X (electronic) Comprehensive Gynecology and Obstetrics ISBN 978-981-15-8170-0 ISBN 978-981-15-8171-7 (eBook) https://doi.org/10.1007/978-981-15-8171-7 © Springer Nature Singapore Pte Ltd. 2021 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neithe
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