Small/Round Cell Lesions

Lesions considered in this chapter include traditional “small blue round cell” neoplasms, specifically Ewing sarcoma/primitive neuroectodermal tumor (ES/PNET) and lymphomas, solitary plasmacytoma/multiple myeloma, and other lesions that tend to be compose

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Frozen Section Library: Bone

Omar Hameed, MBChB University of Alabama at Birmingham, AL, USA

Shi Wei, MD, PhD University of Alabama at Birmingham, AL, USA

Gene P. Siegal, MD, PhD University of Alabama at Birmingham, AL, USA

Omar Hameed, MBChB Associate Professor of Pathology and Surgery Department of Pathology University of Alabama at Birmingham Birmingham, AL, USA [email protected] Shi Wei, MD, PhD Assistant Professor Department of Pathology University of Alabama at Birmingham Birmingham, AL, USA [email protected] Gene P. Siegal, MD, PhD R. W. Mowry Endowed Professor of Pathology Director, Division of Anatomic Pathology Executive Vice-Chair – Pathology, UAB Health System Department of Pathology University of Alabama at Birmingham Birmingham, AL, USA [email protected]

ISSN 1868-4157 e-ISSN 1868-4165 ISBN 978-1-4419-8375-6 e-ISBN 978-1-4419-8376-3 DOI 10.1007/978-1-4419-8376-3 Springer New York Dordrecht Heidelberg London Library of Congress Control Number: 2011921258 © Springer Science+Business Media, LLC 2011 All rights reserved. This work may not be translated or copied in whole or in part without the written permission of the publisher (Springer Science+Business Media, LLC, 233 Spring Street, New York, NY 10013, USA), except for brief excerpts in connection with reviews or scholarly analysis. Use in connection with any form of information storage and retrieval, electronic adaptation, computer software, or by similar or ­dissimilar methodology now known or hereafter developed is forbidden. The use in this publication of trade names, trademarks, service marks, and similar terms, even if they are not identified as such, is not to be taken as an expression of opinion as to whether or not they are subject to ­proprietary rights. While the advice and information in this book are believed to be true and accurate at the date of going to press, neither the authors nor the editors nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein. Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com)

To my parents, my dearest wife, Chura, and my daughters, Shilan and Sara OH To my loving wife, Mei, for her unending support, and my wonderful children, Johnny and Erica SW To all those who have taught me...my mentors, my trainees and most assuredly my family - from Sandy to Marley and all those in between. GPS

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Series Preface

For over 100 years, the frozen section has been utilized as a tool for the rapid diagnosis of specimens while a patient is undergoing surgery, usually under general anesthesia, as a basis for making immediate treatment decisions. Frozen section diagnosis is often a challenge for the pathologist who must render a diagnosis that has crucial import for the patient in a minimal amount of time. In addition to the need