Successful treatment of hepatocellular carcinoma by laparoscopic radiofrequency ablation in a patient with hemophilia A
- PDF / 1,084,891 Bytes
- 7 Pages / 595.276 x 790.866 pts Page_size
- 13 Downloads / 181 Views
CASE REPORT
Successful treatment of hepatocellular carcinoma by laparoscopic radiofrequency ablation in a patient with hemophilia A Rie Goka · Naoki Morimoto · Kouichi Miura1 · Shunji Watanabe · Yoshinari Takaoka · Hiroaki Nomoto · Mamiko Tsukui · Takeshi Fujieda · Hiroshi Maeda1 · Naoto Sato1 · Tsukasa Ohmori2 · Norio Isoda · Hironori Yamamoto Received: 11 February 2020 / Accepted: 16 May 2020 © Japanese Society of Gastroenterology 2020
Abstract Percutaneous radiofrequency ablation (RFA) is a good indication for hepatocellular carcinoma (HCC) in cases involving ≦ 3 tumors of ≦ 30 mm in size, many hepatologists are hesitant to perform the procedure for patients with hemorrhagic disorders. We herein report the successful treatment of HCC by laparoscopic RFA in a patient with hemophilia A. A 48-year-old man with moderate form of hemophilia A had a single HCC at segment 8. To perform laparoscopic RFA safely, recombinant factor VIII (rFVIII) was administered to maintain factor VIII activity (FVIII:C) > 80% on the operation day and > 40% for 6 days after the operation in accordance with the guidelines. A total of 23,000 units of rFVIII was used. Laparoscopic RFA was completed with an operation time of 105 min and
Data Loading...
