Supportive Care in Pediatric Oncology A Practical Evidence-Based App

Much of the gains in survival over the last 50 years in pediatric oncology have occurred through successively more intensive treatment regimens and concomitant improvement in the supportive care required to manage the complications of such regimens. 

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James H. Feusner Caroline A. Hastings Anurag K. Agrawal Editors

Supportive Care in Pediatric Oncology A Practical Evidence-Based Approach

Pediatric Oncology

Each volume of the series “Pediatric Oncology” covers the whole spectrum of the disease concerned, from research issues to clinical management, and is edited by internationally highly respected experts in a comprehensive and clearly structured way. The user-friendly layout allows quick reference to in-depth information. The series is designed for all health-care personnel interested in high-level education in pediatric oncology.

James H. Feusner • Caroline A. Hastings Anurag K. Agrawal Editors

Supportive Care in Pediatric Oncology A Practical Evidence-Based Approach

Editors James H. Feusner Hematology/Oncology Children’s Hospital and Research Center Oakland Oakland, CA USA

Anurag K. Agrawal Hematology/Oncology Children’s Hospital and Research Center Oakland Oakland, CA USA

Caroline A. Hastings Hematology/Oncology Children’s Hospital and Research Center Oakland Oakland, CA USA

ISSN 1613-5318 ISSN 2191-0812 (electronic) ISBN 978-3-662-44316-3 ISBN 978-3-662-44317-0 (eBook) DOI 10.1007/978-3-662-44317-0 Springer Heidelberg New York Dordrecht London Library of Congress Control Number: 2014959419 © Springer Berlin Heidelberg 2015 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. Exempted from this legal reservation are brief excerpts in connection with reviews or scholarly analysis or material supplied specifically for the purpose of being entered and executed on a computer system, for exclusive use by the purchaser of the work. Duplication of this publication or parts thereof is permitted only under the provisions of the Copyright Law of the Publisher's location, in its current version, and permission for use must always be obtained from Springer. Permissions for use may be obtained through RightsLink at the Copyright Clearance Center. Violations are liable to prosecution under the respective Copyright Law. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. While the advice and information in this book are believed to be true and accurate at the date of publication, neither the authors nor the editors nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein. Printed on acid-free pa