Suppressing the Mind Anesthetic Modulation of Memory and Consciousne
By suppressing memory and consciousness - two components of the mind - anesthetics provide great relief to surgical patients and elicit wonder in clinicians and scientists. To-date we do not fully understand the mechanisms by which these effects are achie
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Edited by
ANTHONY HUDETZ
ROBERT PEARCE
Suppressing the Mind
For further volumes: http://www.springer.com/series/7678
Anthony Hudetz · Robert Pearce Editors
Suppressing the Mind Anesthetic Modulation of Memory and Consciousness
Editors Anthony Hudetz Department of Anesthesiology Medical College of Wisconsin 8701 Watertown Plank Road Milwaukee WI 53226 USA [email protected]
Robert Pearce Department of Anesthesiology University of Wisconsin, Madison B6/319 Clinical Science Center 600 Highland Avenue Madison WI 53792 USA [email protected]
ISBN 978-1-60761-463-0 e-ISBN 978-1-60761-462-3 DOI 10.1007/978-1-60761-462-3 Library of Congress Control Number: 2009938710 © Humana Press, a part of Springer Science+Business Media, LLC 2010 All rights reserved. This work may not be translated or copied in whole or in part without the written permission of the publisher (Humana Press, c/o Springer Science+Business Media, LLC, 233 Spring Street, New York, NY 10013, USA), except for brief excerpts in connection with reviews or scholarly analysis. Use in connection with any form of information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed is forbidden. The use in this publication of trade names, trademarks, service marks, and similar terms, even if they are not identified as such, is not to be taken as an expression of opinion as to whether or not they are subject to proprietary rights. While the advice and information in this book are believed to be true and accurate at the date of going to press, neither the authors nor the editors nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein. Printed on acid-free paper springer.com
Foreword
Anesthetics produce a reversible state of unconsciousness accompanied by anterograde amnesia. This remarkable phenomenon brings great relief to surgical patients and wonder to clinicians and scientists. To date, we do not fully understand the mechanisms by which anesthetics ablate conscious sensation and memory. We are, however, making progress. This book presents original results as well as overviews of the current state of knowledge of the problem. It is authored by investigators who know the field well; their research at a number of levels has contributed substantially to our current understanding of anesthetic modulation of memory and consciousness. Most of the contributors were presenters at two workshops organized by Dr. Pearce and Dr. Hudetz at the 40th Annual Winter Conference on Brain Research, held at Snowmass Village, Colorado, from January 27 through February 2, 2007. One workshop focused on anesthetic modulation of consciousness and another on anesthetic modulation of memory. Seven of the chapters are based on material presented at these symposia – appropriately updated with new relevant findings. This information is supplemented by chapters on anes
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