Surgical mask on top of high-flow nasal cannula improves oxygenation in critically ill COVID-19 patients with hypoxemic
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RESEARCH
Surgical mask on top of high‑flow nasal cannula improves oxygenation in critically ill COVID‑19 patients with hypoxemic respiratory failure Virginie Montiel1* , Arnaud Robert1, Annie Robert2, Anas Nabaoui1, Tourneux Marie1, Natalia Morales Mestre1,3, Maerckx Guillaume1,3, Pierre‑François Laterre1 and Xavier Wittebole1
Abstract Objective: Critically ill patients admitted in ICU because of COVID-19 infection display severe hypoxemic respiratory failure. The Surviving Sepsis Campaign recommends oxygenation through high-flow nasal cannula over non-invasive ventilation. The primary outcome of our study was to evaluate the effect of the addition of a surgical mask on a highflow nasal cannula system on oxygenation parameters in hypoxemic COVID-19 patients admitted in ICU who do not require urgent intubation. The secondary outcomes were relevant changes in PaCO2 associated with clinical modifica‑ tions and patient’s feelings. Design: We prospectively assessed 21 patients admitted in our mixed Intensive Care Unit of the Cliniques Universi‑ taires Saint Luc. Main results: While FiO2 was unchanged, we demonstrate a significant increase of PaO2 (from 59 (± 6), to 79 mmHg (± 16), p
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