Surgical Treatment of Hilar and Intrahepatic Cholangiocarcinoma

Cholangiocarcinoma is the second most frequent primary neoplasm of the liver and its incidence is increasing in Western countries. These neoplasms arise from the biliary tract and can be categorized according to their anatomical location as intrahepatic a

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Alfredo Guglielmi • Andrea Ruzzenente • Calogero Iacono

Surgical Treatment of Hilar and Intrahepatic Cholangiocarcinoma In cooperation with Luigi Marchiori Silvia Pachera Luca Bortolasi Riccardo Manfredi Paola Capelli

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Alfredo Guglielmi Andrea Ruzzenente Calogero Iacono General Surgery A, Department of Surgery and Gastroenterology University Hospital G.B. Rossi Verona, Italy in cooperation with Luigi Marchiori, Silvia Pachera, Luca Bortolasi General Surgery A, Department of Surgery and Gastroenterology University Hospital G.B. Rossi Verona, Italy Riccardo Manfredi Department of Radiology University Hospital G.B. Rossi Verona, Italy Paola Capelli Department of Pathology University Hospital G.B. Rossi Verona, Italy The publication and the distribution of this volume have been supported by the Italian Society of Surgery Library of Congress Control Number: 2007931745 ISBN 978-88-470-0728-4 Milan Heidelberg New York e-ISBN 978-88-470-0729-1 Springer is a part of Springer Science+Business Media springer.com © Springer-Verlag Italia 2008 This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, re-use of illustrations, recitation, broadcasting, reproduction on microfilms or in other ways, and storage in data banks. Duplication of this publication or parts thereof is only permitted under the provisions of the Italian Copyright Law in its current version, and permission for use must always be obtained from Springer. Violations are liable for prosecution under the Italian Copyright Law. The use of general descriptive names, registered names, trademarks, etc., in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. Product liability: The publisher cannot guarantee the accuracy of any information about dosage and application contained in this book. In every individual case the user must check such information by consulting the relevant literature. Cover design: Simona Colombo, Milan, Italy Typesetting: Graphostudio, Milan, Italy Printing and binding: Arti Grafiche Nidasio, Assago, Italy Printed in Italy Springer-Verlag Italia S.r.l. – Via Decembrio 28 – I-20137 Milan

Foreword

In the 10 years since the presentation of Gazzaniga’s excellent monograph on extrahepatic biliary tumours at the SIC Congress in 1997, interesting developments in the field have pressed upon us an undoubted need to reassess the complex topic of hepatobiliary surgery. It is therefore with great pleasure that, at the proposal of the Steering Committee of the Italian Society of Surgery (SIC), we present to Italian surgeons this monograph on the treatment of hilar and intrahepatic cholangiocarcinoma, prepared by Alfredo Guglielmi, professor and chairman of Surgical Department A at the University School of Medicine of Verona, and his colleagues. The volume is divided into two parts. The first relates to hil