Survival Analysis A Self-Learning Text
This text on smvival analysis methods contains the following chapters: 1 Introduction to Smvival Analysis 2 Kaplan-Meier Survival Curves and the Log-Rank Test 3 The Cox Proportional Hazards Model and Its Characteristics 4 Evaluating the Proportional Hazar
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Statistics in the Health Sciences Manton/Singer/Suzman: Forecasting the Health of Elderly Populations Salsburg: The U se of Restricted Significance Tests in Clinical Trials Kleinbaum: Logistic Regression: A Self-Learning Text Kleinbaum: Survival Analysis: A Self-Learning Text
David G. Kleinbaum
SURVIVAL
A Self-Learning Text
Springer
David G. Kleinbaum Department of Epidemiology Emory University Atlanta, GA 30333 USA Series Editors
K. Dietz
M. Gail
K. Krickeberg
B. Singer
Institut für Medizinische Biometrie Universität Tübingen West Bahnhotstrasse 55 7400 Tübingen Germany 3 Rue de L'Estrapade 75005 Paris France
National Cancer Institute Rockville, MD 20892 USA
Office of Population Research Princeton University Princeton, NJ 08544 USA
Library of Congress Cataloging-in-Publication Data Kleinbaum, David G. Survival Analysis: a self-learning text / David G. Kleinbaum. p. cm. - (Statistics in the health sciences) Includes bibliographical references and index. ISBN 978-1-4757-2557-5
ISBN 978-1-4757-2555-1 (eBook)
DOI 10.1007/978-1-4757-2555-1 1. Survival analysis (Biometry) I. Title 11. Series: Springer series in statistics. Statistics in the health sciences. R853.S7K543 1995 610'.72-dc20 95-18632
Printed on acid-free paper. © 1996 Springer Science+Business Media New York Originally published by Springer-Verlag New York Inc. in 1996. Softcover reprint of the hardcover 1st edition 1996
All rights reserved. This work may not be translated or copied in whole or in part without the written permission of the publisher (Springer Science+Business Media, LLC), except for brief excerpts in connection with reviews or scholarly analysis. Use in connection with any form of information storage and retrievaI, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed is forbidden. The use of general descriptive names, trade names, trademarks, etc., in this publication, even if the former are not especially identified, is not to be taken as a sign that such names, as understood by the Trade Marks and Merchandise Marks Act, may accordingly be used freely by anyone. Production managed by Steven Pisano; manufacturing supervised by Jeffrey Taub. Typeset by Impressions, Inc., Madison, WI.
9 8 7 6 5 4 3 2 1 SPIN 10490574
To my mother, Janet Leventhal Kleinbaum Cohen
Preface This text on smvival analysis methods contains the following chapters: 1 2 3 4 5 6
Introduction to Smvival Analysis Kaplan-Meier Survival Curves and the Log-Rank Test The Cox Proportional Hazards Model and Its Characteristics Evaluating the Proportional Hazards Assumption The Stratified Cox Procedure Extension of the Cox Proportional Hazards Model for TimeDependent Variables
Each chapter contains a presentation of its topic in '1ecture-book" format together with objectives, an outline, key formulae, practice exercises, and a test. The "lecture-book" has a sequence of illustrations and formulae in the left column of each page and a script in the right col
