Synthesis of Heterocycles via Multicomponent Reactions II

Géraldine Masson, Luc Neuville ∙ Carine Bughin ∙ Aude Fayol ∙ Jieping Zhu Multicomponent Syntheses of Macrocycles Thomas J.J. Müller Palladium-Copper Catalyzed Alkyne Activation as an Entry to Multicomponent Syntheses of Heterocycles Rachel Scheffelaar ∙

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Editorial Board: D. Enders S.V. Ley G. Mehta K.C. Nicolaou R. Noyori L.E. Overman A. Padwa S. Polanc l

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Topics in Heterocyclic Chemistry Series Editor: Bert U.W. Maes Recently Published and Forthcoming Volumes

Synthesis of Heterocycles via Multicomponent Reactions II Volume Editors: R.V.A. Orru, E. Ruijter Volume 25, 2010

Synthesis of Heterocycles via Cycloadditions II Volume Editor: A. Hassner Volume 13, 2008

Anion Recognition in Supramolecular Chemistry Volume Editors: P.A. Gale, W. Dehaen Volume 24, 2010

Synthesis of Heterocycles via Cycloadditions I Volume Editor: A. Hassner Volume 12, 2008

Synthesis of Heterocycles via Multicomponent Reactions I Volume Editors: R.V.A. Orru, E. Ruijter Volume 23, 2010 Heterocyclic Scaffolds I: b-Lactams Volume Editor: B. Banik Volume 22, 2010 Phosphorous Heterocycles II Volume Editor: R.K. Bansal Volume 21, 2009 Phosphorous Heterocycles I Volume Editor: R.K. Bansal Volume 20, 2009 Aromaticity in Heterocyclic Compounds Volume Editors: T. Krygowski, M. Cyran´ski Volume 19, 2009 Heterocyclic Supramolecules I Volume Editor: K. Matsumoto Volume 17, 2008 Bioactive Heterocycles VI Flavonoids and Anthocyanins in Plants, and Latest Bioactive Heterocycles I Volume Editor: N. Motohashi Volume 15, 2008 Heterocyclic Polymethine Dyes Synthesis, Properties and Applications Volume Editor: L. Strekowski Volume 14, 2008

Bioactive Heterocycles V Volume Editor: M.T.H. Khan Volume 11, 2007 Bioactive Heterocycles IV Volume Editor: M.T.H. Khan Volume 10, 2007 Bioactive Heterocycles III Volume Editor: M.T.H. Khan Volume 9, 2007 Bioactive Heterocycles II Volume Editor: S. Eguchi Volume 8, 2007 Heterocycles from Carbohydrate Precursors Volume Editor: E.S.H. ElAshry Volume 7, 2007 Bioactive Heterocycles I Volume Editor: S. Eguchi Volume 6, 2006 Marine Natural Products Volume Editor: H. Kiyota Volume 5, 2006 QSAR and Molecular Modeling Studies in Heterocyclic Drugs II Volume Editor: S.P. Gupta Volume 4, 2006 QSAR and Molecular Modeling Studies in Heterocyclic Drugs I Volume Editor: S.P. Gupta Volume 3, 2006

Synthesis of Heterocycles via Multicomponent Reactions II Volume Editors: R.V.A. Orru, E. Ruijter

With contributions by I. Akritopoulou-Zanze  J.B. Bariwal  C. Bughin  S.W. Djuric  A. Fayol  N. Kielland  R. Lavilla  G. Masson  T.J.J. Mu¨ller  L. Neuville  R.V.A. Orru  E. Ruijter  R. Scheffelaar  J.C. Trivedi  E.V. Van der Eycken  J. Zhu

The series Topics in Heterocyclic Chemistry presents critical reviews on “Heterocyclic Compounds” within topic-related volumes dealing with all aspects such as synthesis, reaction mechanisms, structure complexity, properties, reactivity, stability, fundamental and theoretical studies, biology, biomedical studies, pharmacological aspects, applications in material sciences, etc. Metabolism will also be included which will provide information useful in designing pharmacologically active agents. Pathways involving destruction of heterocyclic rings will also be dealt with so that synthesis of specifically functionalized non-hetero