The Adenosine Receptors

This book traces the history of adenosine receptor research from molecular biology to medicinal chemistry to behavior, including their implications in disease and potential strategies as therapeutic targets. It provides the reader with a comprehensiv

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Pier Andrea Borea · Katia Varani  Stefania Gessi · Stefania Merighi  Fabrizio Vincenzi Editors

The Adenosine Receptors

The Receptors Volume 34

Series Editor Giuseppe Di Giovanni Department of Physiology & Biochemistry Faculty of Medicine and Surgery University of Malta Msida, Malta

The Receptors book Series, founded in the 1980’s, is a broad-based and well-­ respected series on all aspects of receptor neurophysiology. The series presents published volumes that comprehensively review neural receptors for a specific hormone or neurotransmitter by invited leading specialists. Particular attention is paid to in-depth studies of receptors’ role in health and neuropathological processes. Recent volumes in the series cover chemical, physical, modeling, biological, pharmacological, anatomical aspects and drug discovery regarding different receptors. All books in this series have, with a rigorous editing, a strong reference value and provide essential up-to-date resources for neuroscience researchers, lecturers, students and pharmaceutical research.

More information about this series at http://www.springer.com/series/7668

Pier Andrea Borea • Katia Varani Stefania Gessi  •  Stefania Merighi Fabrizio Vincenzi Editors

The Adenosine Receptors

Editors Pier Andrea Borea Department of Medical Sciences University of Ferrara Ferrara, Italy

Katia Varani Department of Medical Sciences University of Ferrara Ferrara, Italy

Stefania Gessi Department of Medical Sciences University of Ferrara Ferrara, Italy

Stefania Merighi Department of Medical Sciences University of Ferrara Ferrara, Italy

Fabrizio Vincenzi Department of Medical Sciences University of Ferrara Ferrara, Italy

The Receptors ISBN 978-3-319-90807-6    ISBN 978-3-319-90808-3 (eBook) https://doi.org/10.1007/978-3-319-90808-3 Library of Congress Control Number: 2018948728 © Springer Nature Switzerland AG 2018 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims