The Biophysics of Cell Membranes Biological Consequences

This volume focuses on the modulation of biological membranes by specific biophysical properties. The readers are introduced to emerging biophysical approaches that mimick specific states (like membrane lipid asymmetry, membrane curvature, lipid flip-flop

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Richard M. Epand Jean-Marie Ruysschaert Editors

The Biophysics of Cell Membranes Biological Consequences

Springer Series in Biophysics Volume 19

Series editor Boris Martinac

More information about this series at http://www.springer.com/series/835

Richard M. Epand • Jean-Marie Ruysschaert Editors

The Biophysics of Cell Membranes Biological Consequences

123

Editors Richard M. Epand Biochemistry and Biomedical Sciences McMaster University Hamilton, ON, Canada

Jean-Marie Ruysschaert Sciences Faculty Université Libre de Bruxelles Bruxelles, Belgium

ISSN 0932-2353 ISSN 1868-2561 (electronic) Springer Series in Biophysics ISBN 978-981-10-6243-8 ISBN 978-981-10-6244-5 (eBook) DOI 10.1007/978-981-10-6244-5 Library of Congress Control Number: 2017952612 © Springer Nature Singapore Pte Ltd. 2017 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer Nature Singapore Pte Ltd. The registered company address is: 152 Beach Road, #21-01/04 Gateway East, Singapore 189721, Singapore

Preface

Chapters in this volume discuss several aspects of the physical properties of biological membranes and how these properties influence their functioning. The reviews emphasize the mechanisms that result in these changes in membrane properties and function. One of the rapidly developing areas in membrane biophysics in recent years has been the role of transbilayer lipid asymmetry. It is known that the lipid composition of the bilayer of a biological membrane is very different for the two monolayers that compose this bilayer. Most studies of model membranes have employed membranes with identical composition for the two monolayers. There are technical difficulties in making model membranes with transbilayer asymmetry. Chapter 1 describes the methods that are being develop