The first consecutive 5000 patients with Coronavirus Disease 2019 from Qatar; a nation-wide cohort study
- PDF / 1,246,158 Bytes
- 11 Pages / 595.276 x 790.866 pts Page_size
- 15 Downloads / 213 Views
RESEARCH ARTICLE
Open Access
The first consecutive 5000 patients with Coronavirus Disease 2019 from Qatar; a nation-wide cohort study Ali S. Omrani1* , Muna A. Almaslamani1, Joanne Daghfal1, Rand A. Alattar1, Mohamed Elgara2, Shahd H. Shaar1, Tawheeda B. H. Ibrahim1, Ahmed Zaqout1, Dana Bakdach3, Abdelrauof M. Akkari3, Anas Baiou3, Bassem Alhariri4, Reem Elajez5, Ahmed A. M. Husain1, Mohamed N. Badawi1, Fatma Ben Abid1, Sulieman H. Abu Jarir1, Shiema Abdalla1, Anvar Kaleeckal6, Kris Choda6, Venkateswara R. Chinta6, Mohamed A. Sherbash7, Khalil Al-Ismail1, Mohammed Abukhattab1, Ali Ait Hssain3, Peter V. Coyle8, Roberto Bertollini9, Michael P. Frenneaux10, Abdullatif Alkhal1 and Hanan M. Al-Kuwari9
Abstract Background: There are limited data on Coronavirus Disease 2019 (COVID-19) outcomes at a national level, and none after 60 days of follow up. The aim of this study was to describe national, 60-day all-cause mortality associated with COVID-19, and to identify risk factors associated with admission to an intensive care unit (ICU). Methods: This was a retrospective cohort study including the first consecutive 5000 patients with COVID-19 in Qatar who completed 60 days of follow up by June 17, 2020. The primary outcome was all-cause mortality at 60 days after COVID-19 diagnosis. In addition, we explored risk factors for admission to ICU. Results: Included patients were diagnosed with COVID-19 between February 28 and April 17, 2020. The majority (4436, 88.7%) were males and the median age was 35 years [interquartile range (IQR) 28–43]. By 60 days after COVID-19 diagnosis, 14 patients (0.28%) had died, 10 (0.2%) were still in hospital, and two (0.04%) were still in ICU. Fatal COVID-19 cases had a median age of 59.5 years (IQR 55.8–68), and were mostly males (13, 92.9%). All included pregnant women (26, 0.5%), children (131, 2.6%), and healthcare workers (135, 2.7%) were alive and not hospitalized at the end of follow up. A total of 1424 patients (28.5%) required hospitalization, out of which 108 (7.6%) were admitted to ICU. Most frequent co-morbidities in hospitalized adults were diabetes (23.2%), and hypertension (20.7%). Multivariable logistic regression showed that older age [adjusted odds ratio (aOR) 1.041, 95% confidence interval (CI) 1.022–1.061 per year increase; P < 0.001], male sex (aOR 4.375, 95% CI 1.964–9.744; P < 0.001), diabetes (aOR 1.698, 95% CI 1.050– 2.746; P 0.031), chronic kidney disease (aOR 3.590, 95% CI 1.596–8.079, P 0.002), and higher BMI (aOR 1.067, 95% CI 1.027–1.108 per unit increase; P 0.001), were all independently associated with increased risk of ICU admission. (Continued on next page)
* Correspondence: [email protected] 1 Communicable Diseases Center, Hamad Medical Corporation, Doha, QatarPO Box 3050 Full list of author information is available at the end of the article © The Author(s). 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as
Data Loading...
